奈米生實驗室                                                                        

Nano Biomedicine  Laboratory 

(Hui-Fen Wu's Group)

 

 

吳慧芬老師

中山大學化學系專任教授

 

中山大學特聘教授

中山大學醫學科技研究所合聘教

中山大學海洋生物科技博士學程合聘教授

高雄醫學大學藥學系合聘教授

 

E-mail: hwu@faculty.nsysu.edu.tw

高雄市鼓山區蓮海路70  

國立中山大學化學系

實驗室:SC4030室

電話:(07)5252000-3916

老師研究室:SC4026

電話:(07)5252000-3955

傳真:(07)5253908

 

獎勵/榮譽:

台灣化學感測器科技協會105年度學術傑出獎

2012國際傑出發明家獎-學術國光獎章

台灣化學感測器科技協會103年度傑出論文獎

中山大學102學年度研究傑出獎

中山大學103-107學年度 特聘教授(學術研究類)

中山大學101年論文被引用獎勵

中山大學102,101,100年學術研究績優教師

97,99,101,102,103,104,105年國立中山大學化學系研究績優獎

2007-2012國立中山大學研究獎勵

2009年國立中山大學教學研究獎勵

1997-2006淡江大學專題研究成效卓著獎

1997-2006淡江大學研究獎勵

1997年國科會甲等研究獎

Marquis Who's Who (2009)

30th Pearl Anniversary Edition of Who’s Who in the World2013,

2014 Who's Who in the World-distinguishes as a star

Hobby:

Music in a group, Table tennis

                  

                                                                       

                                                                               

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Congratulation for our previous Lab members obtained academic positions:

Judy (post-doc), Assistant Professor in Korea.

Mani (post-doc), Assistant Professor in Korea.

Hasan (PhD), Assistant Professor in a Medical University.

Hani (Master), Lecturer in Egypt.

Anita (post-dco), Assistant Professor in India.

Suresh Kumar (post-doc), Assistant Professor in India.

Shrivas (post-doc), Assistant Professor in India.

Lokesh (post-doc), Assistant Professor in India.

Faheem (post-doc), Assistant Professor.

 

Congratulation for our Lab members obtained PhD degrees:

Hasan (Sep 2008 -Jan 2013), Raju (Sep 2010-Aug 2015), Mukesh (Sep 2011-Jan 2016),

Khan (Sep 2011-Jan 2016), Abu (Sep 2011-May 2016).

  

 

 

 

 

 

本實驗獲得國際期刊封面報/期刊上作者介紹的榮譽:

 

   

 

                                 

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Our Lab is an internaitonal Lab and also a multidisciplinary Lab and  working on cross field research so the principle investigator: Professor Wu is currently the distinguished professor of NSYSU and also has been co-appointed to other departments including College of pharmacy, Kaohsiung medical University, Institute of medical sciences, NSYSU; Doctoral degree of marine biotechnology, NSYSU ; those master and PhD students who are interested to join our Lab, can contact Professor Wu by email for details. My Lab has master and PhD students from Taiwan, India, China, and Egypt. Prof. Wu has also associated the Universities of Indonesia, Philippine, Vietnam, Israel and Thailand and hope to receive foreignal students from the above countries.

 

 

目前研究:

奈米生物醫學

合成新的奈米中孔洞/量子點,Graphene Quantum Dots 複合材料應用藥物傳輸多類型的癌症治療,如:胰臟癌,腦癌,乳癌,肝癌,肺癌治療,神經科學(Neuro Science)疾病研究(:阿茲海默症Alzheimer's Disease) 

生醫影像科技開發

以雷射脫附質譜的技術,研究快速及靈敏的活體細菌動力學

合成米粒子在藥物的應用.

米粒子在奈米藥物系統的開發.

製造生物質譜晶片快速檢驗感染菌.

SERS-Raman 生物反應器

 

癌症診斷/治療分析法

癌症幹細胞檢測及奈米粒子治療癌症研究.

功能性量子點(Carbon nanodots)藥物傳輸(drug delivery)&癌症治療

功能性Graphene奈米粒子於藥物(drug delivery)&癌症治療

SERS-Raman 生物反應器快速檢驗癌症

 

奈米/細菌,微生物分析法

高分子量子點(Polymer dots)合成及應用細菌研究.
金黃色葡萄球菌感染老鼠之檢驗及奈米粒子應用抗菌之研究.

細菌之生物膜(biofilm)的檢驗分析.

米粒子/量子點應用細菌之生物膜的分析

半導體米粒子合成,量子點合成,表面修飾及應用細菌蛋白質體學.

 

海洋生物科技

污染/水質分析,Hg毒物分析

 

更多實驗室詳細資訊請參考以下連結 (Link to below for more information):

主要儀器介紹 (Introduction of ESI-MS and MALDI-MS)              

實驗室儀器設備 (Selective Lab Instruments)              

實驗室成員相片 (Lab Members and Photos)

實驗室成員論文及榮譽 (Lab Members Thesis and Honors)                 

The Lab work has been focused on Nano-Biomedicine and medical projects using nanotechnology.The current interests are: (1) Developing drug delivery techniques using nanotechnology for various cancer treatment such as pancreas, brain and breast cancers.(2) Early diagnosis of cancer stem cells. (3) Nanotechnology for pathogenic bacteria analysis. (4) Novel methods for medical technology. (5) Marine biotechnology for metal pollution analysis from seawater and fish. The lab welcomes motivated applicants from international countries for post-doc, PhD and master students. Contact Prof. Wu for application details.

 

 

研究成果:

已發表200SCI國際學術期刊論文,17本邀請英文書籍專章之撰寫,其中13

書籍專章已出版,已核准7項專利, 7篇論文被選封面報導,邀請回顧論文13篇

,編輯委員論文2篇,前瞻論文2篇.

 

擔任學術期刊編輯委員:

Associate Editor: Journal of integrated OMICS (2010~)

Editorial Board: Chemistry (the Chin. Chem. Soc., Taipei), (2008-2010).

Editorial Board: Journal of Analytical Methods in Chemistry (2010~) Hindawi Publishing Corporation, USA.

Editorial Board: American Journal of Analytical Chemistry (2011~) Scientific Research Publishing Inc, USA.

Editorial Board: Journal of Biotechnology & Biomaterials (2011~) OMICS publishing group.

 

Editorial Board: Journal of Biochips & Tissue Chips (2012~)

Editorial Board: Spectroscopy: An International Journal (2012~) Hindawi Publishing Corporation, USA.

Editorial Board and Organizing Committee: International Journal of Cancer Studies & Research (2012~), SciDoc Publishers, USA.

Editorial Board: American Journal of Cancer Review (2012~), USA.

Editorial Board: American Journal of Cancer Science (2012~), USA.

Editorial Board: International Journal of Applied Chemical Sciences Research (2014~),USA

Editorial Board: Scholarena Journal of Biotechnology (2014~),USA.

 

Editorial Board: Journal of Biochemistry and Molecular Biology Research, (2014~),Hung-Kong.

 

Editorial Board: International Journal of Neurology Research, (2014~),Hung-Kong.

 

Editorial Board: Austin Proteomics, (2016, Mar~), Austin Publishing Group, USA

 

Book Chapters:

 

1.      Suresh Kailasa, Hui-Fen Wu*, Comprehensive Sampling and Sample Preparation. Volume 3, Chapter title: Inorganic Contaminants: Sample Preparation Approaches. Pawliszyn, J.; Le, X. C.; Li, X-F.; Lee, H. K.; Eds; Elsevier, Academic Press: Oxford, UK, 2012, 743–782. (With author’s photo and biography).

2.      Suresh Kailasa, Hui-Fen Wu*, Vaibhavkumar Mehta, Quantum Dots: Applications, Synthesis and Characterization. Chapter 5: Prospects of Engineering Quantum Dots Applications in Ultrasensitive Assays, Nova Science Publishers, 2012, 69-109.

3.      Suresh Kailasa, Hui-Fen Wu*, Cysteine: Biosynthesis, Chemical Structure and Toxicity. Chapter 3: Toxicity of Cysteine: Towards Biopathways. Editors: Fyodor V Chorkina, Andrey I. Karataev, Nova Science Publishers, 2012, 61-84.

4.      Suresh Kailasa and Hui-Fen Wu*, Lysozymes: Sources, Functions and Role in Disease. Chapter 5: Functions of Lysozymes and their identification of by MALDI-MS. Nova Science Publishers, 2013, 155-169.

5.          Suresh Kailasa, Hui-Fen Wu*, Shang-Da Huang*, Waste Water-Treatment Technologies and Recent Developments . Chapter 5: Recent developments on mass spectrometric techniques for pesticide analysis from waste water. In Tech Publications, 2013, 99-120. (This chapter has 1500 downloads on Dec 14, 2013).

6.     Suresh Kailasa, Karuna A. Rawat, Hui-Fen Wu*, Ionic Liquids in Bioanalysis, ebook entitled “Sample extraction techniques for biological samples: recent advances and novel applications”. Future Science Group, UK, London, 2014, accepted. (with author’s photo and biography).

7.    Suresh Kailasa, Stephanie L. D’souza, Hui-Fen Wu*, Analytical Applications of Nanoparticles in MALDI-MS for Bioanalysis, ebook entitled “Sample extraction techniques for biological samples: recent advances and novel applications” Future Science Group, UK, London, 2014, accepted. (with author’s photo and biography).

8.    Suresh Kailasa, Hui-Fen Wu*, Applications of Carbon Nanomaterials in Cellular Imaging for publication in the Multi-Volume SET (I-XI), Applications of NanoBioMaterials, Volume VIII: NanoBioMaterials in Medical Imaging, Wiley, 2014, accepted.

9.     Hani Abdelhamid, Hui-Fen Wu*, Book:Reference Module in Chemical, Molecular Sciences and    Chemical Engineering, Chapter:11016, Ionic Liquid Matrices for Mass Spectrometry: Design, Synthesis,and Applications, Elsevier, 2014, accepted. 

10.  Suresh Kailasa, Hui-Fen Wu*, Jignesh Kumar, Graphene Science Handbook: Applications and Industrialization. Vol. 6, Chapter title: Graphene-Based Laser Desorption/Ionization Mass Spectrometry: An Approach to Bioanalytical Applications, CRC Press/Taylor&Francis, FL, USA, 2014, in press.

11.   Suresh Kailasa, Hui-Fen Wu*, Chapter 34: Proteomic profiling by nanomaterials-based MALDI mass spectrometry - principles and examples. Book title: Analytical methods and integrated work-flows for Proteomic profiling, Springer, Germany, 2015, 479-496.

12. Suresh Kailasa, Hui-Fen Wu*, Jignesh Kumar, Graphene Science Handbook: Applications and Industrialization. Vol. 6, Chapter title: Graphene-Based Laser Desorption/Ionization Mass Spectrometry: An Approach to Bioanalytical Applications, CRC Press/Taylor&Francis, FL, USA, 2016, in press.

13. Suresh Kailasa, Vaibhavkumar N. Mehta, Nazim Hasan, Hui-Fen Wu*, Applications of Carbon Nanomaterials in Biosensing and Cellular Imaging, Elsevier, 2016, in press (proof 2/23-).

14.  Suresh Kailasa, Vaibhavkumar N. Mehta, Hui-Fen Wu*, Food Preservation: Nanotechnology in the Agri-Food Industry, Volume 6, Chapter 13: Recent Advances in the Direct and Nanomaterials –Based Matrix Assisted Laser Desorption / Ionization Mass Spectrometric Approaches for Rapid Characterization and Identification of Foodborne Pathogens, Edited by Alexandru M Grumezescu, Elsevier, 2016, 449-485.

15.  Hani Abdelhamid, Hui-Fen Wu*, Frontiers in Clinical Drug Research - Alzheimer Disorders Volum 6, Chapter 1, Biological Mass Spectrometry for Diagnosis of Alzheimer’s Disease, 2016, Vol.6, 3-22, Bentham ebooks, eBook Reference No: 9781681083391-16-1038.

16.  Green synthetic approaches for fluorescent carbon dots and their analytical applications, Suresh Kumar Kailasa, Jigna R. Bhamore, Hui-Fen Wu*, Elsevier, 2016, invited, due Mar, 30, 2017.

17.   Suresh Kailasa, Hui-Fen Wu*, Nanomaterials and Chromatography, Elsevier, 2016, invited.

 

 

Patents:

    Hui-Fen Wu, Suresh Kailasa, Nazim Hasan, Apparatus and method of liquid nitrogen assisted spray ionization mass spectrometry. 發明專利核准審定書(學校編號101034TW),台灣發明專利No.101129644 (101/8/16 applied-103/10/28 issued).

 

       Hui-Fen Wu, Judy Gopal, Muthu Manikandan, Nazim Hasan, Bacterio-toxicity/compatibility of Platinum nanoparticles, 2013, Jan. No.: 101081TW. 台灣發明專利.

 

       Hui-Fen Wu, Judy Gopal, Hani Abdelhamid, Pei-Yang Hua, Chitosan nanomagnets for effective extraction and sensitive mass spectrometric detection of pathogenic bacterial endotoxin from human urine, 2013, Mar. No: 102027TW. 台灣發明專利.

 

       Hui-Fen Wu, Muthu Manikandan, Nazim Hasan, PK1322, 鉑奈米粒子用於製備治療癌症藥物的用途, 發明專利核准審定書(學校編號102028TW), Platinum nanoparticles for treatment of cancer,台灣發明專利, No.102137386 (102/10/16 applied-104/7/20 issued).

       Hui-Fen Wu, Hani Abdelhamid, PK13231, 石墨烯磁性甲殼素聚合物之用途,發明專利核准審定書(學校編號102039TW), Graphene magnetic chitosan and its use. 台灣發明專利,No.102138937 (102/10/28 applied-104/6/17 issued).

      Hui-Fen Wu, Hani Abdelhamid, Furoic Acids as new matrices for matrix assisted laser desorption/ionization mass spectrometry, Taiwan Patent applied 2013, May. 台灣發明專利 (104/9 issued).

          Hui-Fen Wu, Hani Abdelhamid, 甲芬那酸為新基質之用途Mefenamic acids as a new matrice for matrix assisted laser desorption/ionization mass spectrometry, Taiwan Patent, 2016, March issued. 台灣發明專利

Publication list (期刊論文):  *Corresponding author, citation to 2014/11/1)

2017

1.     Hani Abdelhamid, Abou Talib, Hui-Fen Wu*, One pot synthesis of gold - carbon dots nanocomposite and its application for cytosensing of metals for cancer cells. Talanta, 2017, accepted (11/15).

2.    Hani Abdelhamid,  Y. C. Lin, Hui-Fen Wu*, Thymine Chitosan Nanomagnets for Specific  Preconcentration of Mercury (II) prior to Analysis Using SELDI-MS, Microchimica Acta, 2017, Accepted (IF 4.81, 1/9).

2016

1.      Sunil Pandey, Abou Talib, M. Mukeshchand Thakur, M. Shahnawaz Khan, Mukesh Lavkush Bhaisare, Gangaraju Gedda, Hui-Fen Wu*, Tellurium Platinate Nano-worms for Photo-thermal and photodynamic therapy of Cancer cells: A paradigm shift in treatment of cancer cells using composite metal alloys, Journal of Materials Chemistry B, 2016, accepted.

2.      Mukesh Bhaisare; Gangaraju Gedda; Shahnawaz Khan; Hui-Fen Wu*, Fluorimetric detection of pathogenic bacteria using Magnetic carbon dots", Analytical Chimia Acta, 2016, accepted.

3.      Hani Abdelhamid*, Hui-Fen Wu*, Gold nanoparticles assisted laser desorption/ionization mass  spectrometry and applications: from simple molecules to intact cells, Analytical and Bioanalytical Chemistry, 2016, accepted.

4.      Muthu Manikandan, Hui-Fen Wu*, Bio-mimicked gold nanoparticles with complex fetal bovine serum as sensors for single cell MALDI MS of cancer cell and cancer stem cell. Sensors & Actuators: B. Chemical, 2016, accepted (IF4.097/4.286, 3/56, 5.36%.).

5.      Judy Gopal, Hani Abdelhamid, Jhih-Huan Huang, Hui-Fen Wu*, Nondestructive detection of the freshness of fruits and vegetables using gold and silver nanoparticle mediated graphene enhanced Raman spectroscopy. Sensors & Actuators: B. Chemical, 2016, Mar, 224, 413-424 (IF4.097/4.286, 3/56, 5.36%.).

6.      Gangaraju Gedda, Chun-Yi Lee, Yu-Chih Lin, Hui-Fen Wu*, Green synthesis of Carbon dots from prawn shells for highly selective and sensitive detection of copper ions, Sensors & Actuators: B. Chemical, 2016, Mar, 224, 396-403 (IF4.097/4.286, 3/56, 5.36%.).

7.      Mukesh L. Bhaisare, Bo-Sgum Wu, Mon-Chun Wu, Mei-Hwuy Tseng, Hui-Fen Wu*, MALDI MS analysis, disk diffusion and optical density measurements for antimicrobial effect of Zinc Oxide nanorods integrated in Graphene Oxide nanostructures. 2016, 4 (1), 183-194, Biomaterials Science (RSC), (IF3.831/3.831, 10/33, materials science, biomaterials).

8.      Gangaraju Gedda, Sunil Pandey, M Shahnawaz Khan, Abou Talib, Hui-Fen Wu*, Novel synthesis of porous titanium oxide for drug delivery of vinorelbin bitartrate, RSC Advances, 2016, 6, 13145-13151 (IF3.84/3.907).

9.      Nazim Hasan, Nawaz Mohd, Hui-Fen Wu*, CoFe2O4-ZnO Nanoparticles for rapid microwave assisted tryptic digestion of phosphoprotein and phosphopeptides analysis in Matrix Assisted Laser Desorption /Ionization Mass Spectrometry, Rapid Communications in Mass Spectrometry, 2016, Accepted.

10. M Shahnawaz Khan, Mukesh L Bhaisare, Judy Gopal, Hui-Fen Wu*, Highly efficient Gold
       nanorods assisted Laser phototherapy for rapid treatment on mice wound infected by pathogenic
        bacteria, Journal of Industrial and Engineering Chemistry (Elsevier). 2016, Accepted
        (IF3.512/3.021).

11.  M Shahnawaz Khan, Mukesh L Bhaisare, Judy Gopal, Hui-Fen Wu*, Highly efficient Gold nanorods assisted Laser phototherapy for rapid treatment on mice wound infected by pathogenic bacteria, Journal of Industrial and Engineering Chemistry (Elsevier). 2016, Accepted (IF3.512/3.021).

12. Abou Talib, M Shahnawaz Khan, Gangaraju Gedda, Hui-Fen Wu*, Stabilization of Gold Nanoparticles using Natural Plant Gel: A greener step towards biological applications, Journal of Molecular Liquids, 2016, Accepted (IF2.5)

13. Abou Talib, Hui-Fen Wu*, Biomimetic synthesis of Lotus leaf extract-assisted silver nanoparticles and shape-directing role of cetyltrimethylammonium bromide, Journal of Molecular Liquids, 2016, Accepted (IF2.5)

14. Bo-Sgum Wu, Judy Gopal, Pei-Yang Hua, Hui-Fen Wu*, Graphene nanosheet mediated MALDI-MS (GN-MALDI-MS) for rapid, in situ detection of intact incipient biofilm on material surfaces, Materials Science & Engineering C, 2016, Accepted.

15. Nazim Hasan, Zhongxian Guo, Hui-Fen Wu*, Large protein analysis of Staphylococcus aureus and Escherichia coli by MALDI TOF mass spectrometry using amoxicillin functionalized magnetic nanoparticles, Analytical and Bioanalytical Chemistry, 2016, accepted, (IF3.5).

16. Mukesh L. Bhaisare, Krishna Hari Sharma, Jun-Yi Lee, Da-Ren Hang, Hui-Fen Wu*,Synthesis of two-dimensional Molybdenum oxide nanoflakes with various phases and their nano-based characterization, New Journal of Chemistry, 2016, Accepted. 

17. Hani Abdelhamid, Sekar Kumaran, Hui-Fen Wu*,One-pot synthesis of CuFeO2 nanoparticles capped with glycerol and proteomic analysis of their nanocytotoxicity against fungi, RSC Advances, 2016, Accepted.

 

2015

1.      Gangaraju Gedda, Sunil Pandey, Yu-Chih Lin, Hui-Fen Wu*, Antibacterial effect of calcium oxide Nano-plates fabricated from Shrimp shells. Green Chemistry, 2015, 17 (6), 3276-3280 (IF8.02).

2.      Suresh K Kailasa, Hui-Fen Wu*, Nanomaterials-based miniaturized extraction and preconcentration techniques coupled with matrix-assisted laser desorption/ionization mass spectrometry for biomolecules assays, Trends in Analytical Chemistry, 2015, Feb, 65, 54-72. (IF6.612/5Y:7.311, 2/76=2.63%).

3.      Hani Abdelhamid*, Hui-Fen Wu*, Proteomic analysis of the mode of antibacterial action of nanoparticles and their interactions with proteins, Trends in Analytical Chemistry, 2015, Feb, 65, 30-46. (IF6.612/5Y:7.311, 2/76=2.63%).

4.      M. Shahanwaz Khan, Hani Abdelhamid, Hui-Fen Wu*, Near infrared (NIR) laser mediated surface activation of graphene oxide nanoflakes for efficient antibacterial, antifungal and wound healing treatment, Colloids and Surfaces B: Biointerfaces, 2015, accepted. (IF4.287/5Y:4.226).

5.      M. Shahanwaz Khan, Sunil Pandey, Hui-Fen Wu*, Controlled delivery of dopamine hydrochloride using surface modified carbon dots for Neuro diseases, Colloids and Surfaces B: Biointerfaces, 2015, accepted. (IF4.287/5Y:4.226).

6.      Hani Abdelhamid, Hui-Fen Wu*, Synthesis of highly dispersive sinapinic acid @ graphene oxide (SA@GO) and their applications as a novel surface assisted laser desorption/ionization mass spectrometry for proteomics and pathogenic bacteria biosensing, Analyst, 2015, 140, 1555-1565, (IF3.906/4.097, 7/76=9.21%)

8.      Sunil Pandey, Mukeshchand Thakur, Abu Talib, M. Shahanwaz Khan, Mukesh Lavkush Bhaisare, Gangaraju Gedda, Shou-Mei Wu, Hui-Fen Wu*, Laser assisted synthesis of Multi-colored Protein dots and their biological distribution in mice using Dye tracking method: A novel approach to deliver therapeutic payloads to central nervous system, RSC-advances, 2015, 5 (6), 4051-4057 (IF3.708/3.708).

9.      Judy Gopal, Hui-Fen Wu*, A brief case study demonstrating the applicability of MALDI Mass Spectrometry for detecting bacteria in dental samples, RSC Advances, 2015, 5, 14090-14094 (IF3.708/3.708).

10.  Mukesh L. Bhaisare, Sunil Pandey, M. Shawan Khan, Abu Talib, Hui-Fen Wu*, Fluorophotometric Determination of Critical Micelle Concentration (CMC) of Ionic and Non-ionic Surfactants with Carbon Dots via Stokes Shift, Talanta, 2015, 132, 572-578, (IF3.794, 12/73, 16.44%, Chemistry, Analytical).

 

11.  Suresh Kumar Kailasa, Hui-Fen Wu*, Electrospray ionization tandem mass spectrometry for rapid, sensitive and direct detection of melamine in dairy products, Journal of Industrial and Engineering Chemistry (Elsevier), 2015, Jan., 21, 138-144 (IF2.145).

 

12.  Nadeem Khan, Hani Nasser Abdelhamid, Ja-Yi Yan, Fon-Tsai Chung, Detection of Flutamide in pharmaceutical dosage using higher electrospray ionization mass spectrometry (ESI-MS) tandem mass coupled with Soxhlet apparatus, Analytical Chemistry Research (Elsevier), 2015, Accepted.(IF2.0).

 

13.  Judy Gopal, Muthu Manikandan, Hui-Fen Wu*, State of the art nano-platform integrated MALDI-MS impacting resolutions in urinary proteomics, Proteomics Clinical Applications, 2015, accepted.(IF2.6). (Review paper).

 

14.  Hani Abdelhamid, Hui-Fen Wu*, Reduced graphene oxide conjugate thymine (T@rGO) as a new probe for ultrasensitive and selective fluorometric determination of mercury (II) ions, Microchimica Acta, 2015 accepted. (IF3.7).

15.  Judy Gopal, Jararn LN, Khan Shan, Hui-Fen Wu*, MALDI mass spectrometry for probing the anti- Staphylococcal capability of TiO2 nanoparticles via near-UV and laser irradiation, New Journal of Chemistry, 2015, 39, 4909-4918.(IF3.159).

16.  Mukesh L. Bhaisare, Hani Abdelhamid, Hui-Fen Wu*, Facile synthesis of water soluble silver ferrite (AgFeO2) nanoparticles and their biological application as antibacterial agents, RSC-advances, 2015, accepted. (IF3.708).

17.  Lokesh A, Hani Abdelhamid, Mohd Nawaz, Hui-Fen Wu*, Synthesis, characterization and bifunctions of bidentate silver nanoparticle assisted single drop microextraction as a highly sensitive preconcentrating probe for protein analysis , RSC-advances, 2015, 5, 41595-41603. (IF3.708).

18.  Hani Abdelhamid, Hui-Fen Wu*, Synthesis and Multifunctional Applications of Quantum Nanobeads for Label-Free and Selective Metals Chemosening, RSC Advances, 2015, 5, 50494-50504 (IF3.708/3.708).

19.  Mukesh L. Bhaisare, Hui-Fen Wu*, Synthesis of fluorescent carbon dots via microwave carbonization of citric acid in presence of tetraoctylammonium ion and their application to cellular bioimaging. Microchimica Acta, 2015, accepted. (IF3.7).

20.  Hani Abdelhamid, Hui-Fen Wu*, Soft Ionization of Metallo-Mefenamic using Electrospray Ionization Mass Spectrometry. Mass Spectrometry Letters, 2015, accepted.

21.  Suresh Kumar Kailasa, Hui-Fen Wu*, Ionic Liquids in Bioanalysis, Bioanalysis, 2015, accepted. (IF3.027/3.04).

22.  Suresh Kumar Kailasa, Hui-Fen Wu*, Analytical Applications of Nanoparticles in MALDI-MS for Bioanalysis, Bioanalysis, 2015, accepted (IF3.027/3.04).

23. Hani Abdelhamid, Hui-Fen Wu*, Synthesis, Characterization of Quantum Dots and Application in Laser Soft Desorption/Ionization for Labile Metal-Drug Interactions and their Antibacterial Activity, RSC Advances, 2015, Sep, 5, 76107-76115 (IF3.84/3.907).

24. M. Shahanwaz Khan, Mukesh Lavkush Bhaisare, Sunil Pandey, Abu Talib, Suresh K Kailasa, Shou-Mei Wu, Hui-Fen Wu*, Exploring the ability of Water Soluble Carbon dots as matrix for detecting neurological Disorders using MALDI-TOF MS, International Journal of Mass Spectrometry, 2015, Accepted.

25. M Shahnawaz Khan, Mukesh L Bhaisare, Judy Gopal, Hui-Fen Wu*, Highly efficient Gold nanorods assisted Laser phototherapy for rapid treatment on mice wound infected by pathogenic bacteria, Journal of Industrial and Engineering Chemistry (Elsevier). 2015, Accepted (IF3.512/3.021).

26. A biographical Memoir by Gabor A. Somorjai for Leo Brewer, 2015, Former Brewer post-doc Hui-Fen Wu recalls Brewer, Proceedings of the National Academy of Sciences, 2015, Accepted.

2014

1.      Muthu Manikandan, Hani Abdelhamid, Abu Talib, Hui-Fen Wu*, Facile synthesis of gold nanohexagons on graphene templates in Raman spectroscopy for biosensing cancer and cancer stem cells, Biosensors and Bioelectronics, 2014, May, 55, 180-186. (IF6.451, 1/26, 3.85%, Electrochemistry, 4/73, 5.48%, Chemistry, Analytical).(This paper has been downloaded or viewed 605 times (in 40 days) since publication on line on Nov.21, 2013 to Dec.31, 2013).Times cited 1.

2.      Pei-Yang Hua, Muthu Manikandan, Hani Abdelhamid, Hui-Fen Wu*, Graphene nanoflakes as efficient ionizing matrix for MALDI MS based lipodomics of cancer cells and cancer stem cells, Journal of Materials Chemistry B, 2014, 2 (42) 7334-7343. (IF6.626/5Y:6.743).

 

3.      Mukesh L. Bhaisare, Hani Abdelhamid, Bo-Sgum Wu, Hui-Fen Wu*, Rapid and direct MALDI-MS identification of pathogenic bacteria from blood via ionic liquid-modified magnetic nanoparticles (Fe3O4@SiO2), Journal of Materials Chemistry B, 2014, 2 (29), 4671-4683 (IF6.626/6.743, 16/225, 7.11%, Materials Science, Multidisciplinary, a journal in biology and medicine).

 

4.      Steve Haga, Hui-Fen Wu*, Overview of software options for processing, analysis and interpretation of mass spectrometric proteomic data, Journal of mass spectrometry, 2014, Oct, 49 (10), 959-969 (IF3.289, 8/42, 19.05%, Spectroscopy). (Special feature article-perspective, journal cover, author biography特寫文章-觀點論文/封面報導/作者介紹).

 

5.      Hani Abdelhamid, Hui-Fen Wu*, Polymer dots for quantifying the total hydrophobic pathogenic lysates in a single drop. Colloids and Surfaces B: Biointerfaces (Elsevier), 2014, Mar, 115, 51-60 (IF3.55). (This paper has been downloaded or viewed 366 times since publication).Times cited 3.

 

6.      Hani Abdelhamid, M. Shawan Khan, Hui-Fen Wu*, Design, characterization and applications of new ionic liquid matrices for multifunctional analysis of biomolecules: a novel strategy for pathogenic bacteria biosensing, Analytica Chimica Acta, 2014, May, 823, 51-60 (IF 4.555, 5/73, 6.85%).Times cited 1.

 

7.      Hani Abdelhamid, Hui-Fen Wu*, Ultrasensitive, rapid and selective detection of mercury using graphene assisted laser desorption/ionization mass spectrometry, Journal of The American Society for Mass Spectrometry, 2014, May, 25 (5), 861-868. (IF3.594). Times cited 2.

 

8.      Hui-Fen Wu*, Suresh Kailasa, Ja-Yi Yen, Chen-Che Chin, Hsin-Yi Ku, Comparison of SDME with MVPE directly coupled with capillary electrophoresis for extraction and separation of tricyclic antidepressant drugs. 2014, 20, 2071-2076, Journal of Industrial and Engineering Chemistry (Elsevier). (IF2.145).

 

9.      Vaibhavkumar Mehta, Suresh Kailasa and Hui-Fen Wu*, Surface Modified Quantum Dots as Effective Fluorescent Probes for Biomolecule Recognition, Journal of Nanoscience and Nanotechnology, 2014, Jan, 14 (1), 447-459 (with Author Photos and Author Biographies, 作者介紹).Times cited 2.

 

10.  Suresh Kailasa, Hui-Fen Wu*, Advances in nanomaterial-based microwaves and infrared wave-assisted tryptic digestion for ultrafast proteolysis and rapid detection by MALDI-MS, Combinatorial Chemistry & High Throughput Screening (Bentham Science), 2014, Jan, 17 (1) 68-79 (IF1.785).

 

11.  Anandkumar Balakrishnan, Steve W. Haga, Hui-Fen Wu*, Computer Applications Making Rapid Advances in High Throughput Microbial Proteomics (HTMP), Combinatorial Chemistry & High Throughput Screening (Bentham Science), 2014, Feb,17(2), 173-182 (IF1.785).

12.  Hani Abdelhamid, Mukesh Bhaisare, Hui-Fen Wu*, Ceria nanocubic-ultrasonication assisted dispersive liquid-liquid microextraction coupled with matrix assisted laser desorption/ionization mass spectrometry for pathogenic bacteria analysis, Talanta, 2014, Mar, 120, 208-217 (IF3.794, 12/76, 15.79%, Chemistry, Analytical). (This paper has been downloaded or viewed 190 times since publication on line on Dec.11, 2013 to Feb.28, 2014).Times cited 2.

13.  Bo-Sgum Wu, Hani Abdelhamid, Hui-Fen Wu*, Preparation and antibacterial performance of graphene decorated stannous dioxide, RSC-Advances, 2014, 4 (8), 3722-3731 (IF3.7). Times cited 3.

14.  Judy Gopal, Muthu Manikandan, Hui-Fen Wu*, Low cost Aluminium foil platforms for extraction of proteins for rapid mass spectrometric differentiation of the fungal pathogen Aspergillus niger mycelium and spores by In situ gold nanosphere accelerated microwave digestion. RSC-Advances, 2014, 4 (21), 10982-10989.(IF3.708).

15.  Suresh Kumar Kailasa, Hui-Fen Wu*, Recent developments of liquid-phase microextraction techniques directly combined with ESI- and MALDI- mass spectrometric techniques for organic and biomolecule analysis. RSC-Advances, 2014, 4 (31), 16188-16205.(IF3.708)

16.  Hani Abdelhamid, Bo-Sgum Wu, Hui-Fen Wu*, Graphene coated silica applied for high ionization matrix assisted laser desorption/ionization mass spectrometry: A novel approach for environmental and biomolecule analysis, Talanta, 2014, Aug, 126, 27-37 (IF3.794, 12/76, Chemistry, Analytical).

 

17.  Suresh Kumar Kailasa, Hui-Fen Wu*, Recent developments in nanoparticle-based MALDI mass spectrometric analysis of phosphoproteomes. Microchimica Acta, 2014, July, 181 (9-10), 853-864. (IF3.719, 9/76, 11.84%, Chemistry, Analytical).

 

18.  Tzu-Yu Pan, Chun-Chi Wang, Chi-Jen Shih, Hui-Fen Wu, Shyh-Shin Choiu*, Shou-Mei Wu*, Genotyping of intron 22 inversion of factor VIII gene for diagnosis of hemophilia A by inverse-shifting polymerase chain reaction and capillary electrophoresis, Analytical and Bioanalytical Chemistry, 2014, Sep, 406 (22), 5447-5454 (IF3.578/5Y:3.744, 11/76, 14.47%).

 

19.  Muthu Manikandan, Judy Gopal, Nazim Hasan, Hui-Fen Wu*, A nano-patterned self assembled monolayer (SAM) rutile titania cancer chip for rapid, low cost, highly sensitive, direct cancer analysis in MALDI-MS, Talanta, 2014, Dec,130, 78-89 (IF3.511/5Y:3.756, 12/76, 15.78%, Chemistry, Analytical).

20.  Gangaraju Gedda, Sunil Pandey, Mukesh L. Bhaisare, Hui-Fen Wu*, Carbon dots as nanoantennas for anti-inflammatory drug analysis using surface-assisted laser desorption/ionization mass spectrometry in serum, RSC-advances, 2014, 4 (72), 38027-38033.(IF3.708/5Y:3.708). 

21.  Muthu Manikandan, Hui-Fen Wu*, Rapid endophytic bacterial detection by enzyme incorporated MALDI MS, RSC Advances, 2014, Aug, 4 (91), 50233-50240 (IF3.708).

22.  Gangaraju Gedda, Hani Abdelhamid, M. Shawan Khan, Hui-Fen Wu*, ZnO nanoparticle modified polymethyl methacrylate assisted dispersive liquid-liquid micro extraction coupled MALDI-MS for rapid pathogenic bacteria analysis, RSC Advances, 2014, Aug, 4 (86), 45973-45983 (IF3.708).

 

23.  Hani Abdelhamid, Hui-Fen Wu*, Graphene oxide as a nanocarrier for gramicidin (GOGD) for high antibacterial performance. RSC Advances, 2014, Oct, 4 (91), 50035-50046 (IF3.708).

24.  Hani Abdelhamid, Hui-Fen Wu*, Monitoring the metallofulfenamic – bovine serum albumin interactions: A novel method for metallodrug analysis. RSC Advances, 2014, 4, 53768-53776 (IF3.708/3.078).

25.  Hani Abdelhamid, Hui-Fen Wu*, Facile synthesis of nano silver ferrite (AgFeO2) modified with chitosan applied for biothiols separation, Materials Science and Engineering C (Materials for Biological Applications), 2014, Dec, 45, 438-445, (IF2.736/5Y:3.076).

26.  Vaibhavkumar N. Mehta, Suresh Kumar Kailasa*, Hui-Fen Wu, Sensitive and selective colorimetric sensing of Fe3+ ion by using p-amino salicylic acid dithiocarbamate functionalized gold nanoparticles, New Journal of Chemistry (RSC), 2014, 38(4), 1503-1511. (IF2.966)

27.  M. Shawan Khan, Judy Gopal, Hui-Fen Wu*, Probing the cytotoxicity of CdS-MPA and CdSe-MUA QDs on the bacterial pathogen Staphylococcus aureus using MALDI-MS, Analytical Methods (RSC), 2014, May, 6 (14), 5304-5313 (IF1.938).

 

28.  Nazim Hasan, Judy Gopal, Hui-Fen Wu*, Surface pretreatment effects on titanium chips for the adhesion of pathogenic bacteria in the MALDI-MS, Applied Surface Science (Elsevier), 2014, Sep, 314, 56-63 (IF2.112/5Y:2.099).

 

29.  Ramaiyan Sekar, Suresh Kailasa, Yuan-Chin Chen, Hui-Fen Wu*, Electrospray ionization tandem mass spectrometric studies to probe the interaction of Cu(II) with amoxicillin. Chinese Chemical Letters (Elsevier), 2014, Jan, 25 (1), 39-45. (IF1.21).

 

30.  Suresh Kailasa, Hui-Fen Wu*, Rapid quantification of efavirenz in human plasma by electrospray ionization tandem mass spectrometry, Journal of the Chinese Chemical Society, 2014, Apr, 61(4), 437-441.

 

2013

 

1.      Muthu Manikandan, Nazim Hasan, Hui-Fen Wu*, Platinum nanoparticles for photothermal treatment of neuro 2A cancer cells, Biomaterials, 2013, July, 34, 5833-5842 (IF8.415, 1/25, 4%, Materials science, biomaterials).台灣化學感測器

   科技協會103年度傑出論文獎.

 

2.      Judy Gopal, Hani Abdelhamid, Pei-Yang Hua, Hui-Fen Wu*, Chitosan nanomagnets for effective extraction and sensitive mass spectrometric detection of pathogenic bacterial endotoxin from human urine, Journal of Materials Chemistry B, 2013, May 1, 2463-2475 (IF6.626/6.743). (Featured in the Journal Back Cover底頁封面報導).

 

3.      Hani Abdelhamid, Hui-Fen Wu*, Multifunctional graphene magnetic nanosheet decorated with chitosan for hghly sensitive detection of pathogenic bacteria, Journal of Materials Chemistry B, 2013, 1 (32), 3950-3961.

 

4.      Hani Abdelhamid, Hui-Fen Wu*, Probing the interactions of chitosan capped CdS quantum dots with pathogenic bacteria and their biosensing application. Journal of Materials Chemistry B, 2013, 1 (44), 6094-6106 .

 

5.      Judy Gopal, Nazim Hasan, Muthu Manikandan, Hui-Fen Wu*, Bacterio-toxicity/compatibility of Platinum nanospheres, nanocuboids and nanoflowers, Scientific Reports (Nature Publishing Group), 2013, Feb, 3, 1260, DOI:10.1038/srep01260.(IF5.078).

 

6.      Judy Gopal, Nazim Hasan, Hui-Fen Wu*, Fabrication of titanium based MALDI bacterial chip for rapid, sensitive and direct analysis of pathogenic bacteria, Biosensors and Bioelectronics, 2013, Jan, 39, 57-63. (IF6.451, 1/26, 3.85%, Electrochemistry, 4/73, 5.48%, Chemistry, Analytical).

 

7.      Hani Abdelhamid, Judy Gopal, Hui-Fen Wu*, Synthesis and application of ionic liquid matrices for effective pathogenic bacteria analysis in Matrix assisted laser desorption/ionization mass spectrometry, Analytica Chimica Acta, 2013, Mar, 767, 104-111 (IF 4.555, 5/73, 6.85%).

      (Highlighted by Sigma-Aldaich: http://www.sigmaaldrich.com/catalog/papers/23452793

and http://www.sigmaaldrich.com/catalog/product/aldrich/310905?lang=en&region=TW)

 

8.      Nazim Hasan, Faheem Ahmad and Hui-Fen Wu*, Heat stress response of Escherichia coli via NiO nanoparticles in MALDI mass spectrometry. Talanta, 2013, 103, 38-46. (IF3.794, 12/73, 16.44%, Chemistry, Analytical).

 

9.      Muthu Manikandan, Nazim Hasan, Hui-Fen Wu*, Rapid detection of haloarchaeal carotenoids from bacteria via liquid liquid microextraction enabled direct TLC MALDI-MS. Talanta, 2013, Mar, 107, 167-175. (IF3.794, 12/73, 16.44%, Chemistry, Analytical).

 

10.  Judy Gopal, Muthu Manikandan, Nazim Hasan, Chia-Hsun Lee, Hui-Fen Wu*, A comparative study on the mode of interaction of different nanoparticles during MALDI-MS of bacterial cells, Journal of Mass Spectrometry, 2013, Jan, 48, 119-127. (IF3.289, 7/41, 17.07%, Spectroscopy).

 

11.  Suresh Kailasa, Hui-Fen Wu*, Surface-assisted laser desorption-ionization mass spectrometry of oligosaccharides using magnesium oxide nanoparticles as a matrix, Microchimica Acta, 2013, 180 (5), 405-413. (IF3.033, 18/73, 24.66%, Chemistry, Analytical).

 

12.  Faheem Ahmad, Hui-Fen Wu*, Rapid and sensitive detection of bacteria via platinum-labeled antibodies and on-particle ionization and enrichment prior to MALDI-TOF mass spectrometry. Microchimica Acta, 2013, 180 (5), 485-492. (IF3.033, 18/73, 24.66%, Chemistry, Analytical).

 

13.  Ramaiyan Sekar, Suresh Kailasa, Hani Abdelhamid, Yuan-Chin Chen and Hui-Fen Wu*, Probing the metal complexation reaction of tobramycin with copper (II) and iron (III) ions by electrospray ionization mass spectrometry, International Journal of Mass Spectrometry, 2013, Mar, 338, 23-29. (IF2.549, 14/41, 34.15%, Spectroscopy).

 

14.  Suresh Kailasa, Hui-Fen Wu*, Recent Advances in Mass Spectrometry for the Identification of Neurochemicals and their Metabolites in Biofluids, Current Neuropharmacology, 2013, July, 29, 436-464. (IF2.031/5Year:3.084, Hot Topic Issue).

 

15.  Ramaiyan Sekar, Suresh Kailasa, Wen-Shan Li, Han-Chung Wu, Hui-Fen Wu*, Rapid separation of acetophenone and its monohydroxy isomers by capillary electrophoresis, Chinese Chemical Letters (Elsevier), 2013, 24, 833-836. (IF1.21).

 

16.  Muthu Manikandan, Hui-Fen Wu*, Rapid probing the fungicidal and biological role of CdS quantum dots in Saccharomyces cereviciae and Candida utilis by MALDI-TOF MS. Journal of Nanoparticles Research, 2013, July, 15 (7), 1728-1740. (IF3.287/5Y:3.574, 36.36%, Nanoscience & Nanotechnology).

 

17.  Suresh Kailasa, Hui-Fen Wu*, Surface modified BaTiO3 Nanoparticles as the matrix for phospholipids and as extracting probes for LLME of hydrophobic proteins in Escherichia coli by MALDI-MS, Talanta, 2013, 114, 283-290. (IF3.794, 12/73, 16.44%, Chemistry, Analytical).

 

18.  Hani Abdelhamid, Hui-Fen Wu*, Furoic and Mefenamic acids as new matrices for drug and peptide analysis by matrix assisted laser desorption/ionization mass spectrometry, Talanta, 2013, Oct, 115, 442-450. (IF3.794, 12/73, 16.44%, Chemistry, Analytical).

19.  Muthu Manikandan, Hui-Fen Wu*, Rapid differentiation and quantification of live/dead cancer cells using differential photochemical behavior of acridine orange, Photochemical & Photobiological Sciences (RSC), 2013, 12 (11), 1921-1926. (Journal Front Cover 封面報導, IF2.9, 33%, Chemistry, Physical).

20.  Suresh Kailasa, Hui-Fen Wu*, Single drop microextraction for bioanalysis: present and future. Bioanalysis, 2013, Nov, 5 (21), 2593-2596 (IF3.223, 15/59=25.42%, Chemistry/Medical), Editorials Article (with Author Photo).

 

21.  Suresh Kailasa, Kuang-Hung Cheng, Hui-Fen Wu*, Semiconductor Nanomaterials-based Fluorescence Spectrometric and MALDI Mass Spectrometric Approaches to Proteome Analyses. Materials, 2013, 6, 5763-5795 (IF2.247).

22.  Bo-Sgum Wu, Hui-Fen Wu*, Nanomaterials based biosensors for bacteria and cancer study, Chemistry (the Chin. Chem. Soc., Taipei), 2013, 71, No3, 213-231.

2012

 

1.  Muthu Manikandan, Hui-Fen Wu*, Nazim Hasan, Cell population based mass spectrometry using platinum nanodots for algal and fungal studies. Biosensors and Bioelectronics, 2012, May, 35, 493-497. (IF5.602, 1/26, 3.85%, Electrochemistry, 4/73, 5.48%, Chemistry, Analytical, Times cited 1).

 

2.  Chia-Hsun Lee, Judy Gopal, Hui-Fen Wu*, Ionic solution and nanoparticle assisted MALDI-MS as bacterial biosensors for rapid analysis of yogurt, Biosensors and Bioelectronics, 2012, Jan, 31, 77-83  (IF5.602, 1/26, 3.85%, Electrochemistry, 4/73, 5.48%, Chemistry, Analytical). Highlighted in the featured article of “Advances in Engineering”, 2012. (http://advancesinengineering.com/page/2/)

 

3.  Faheem Ahmad, Mansoor Siddiqui, Olubukola Babalola, Hui-Fen Wu*, Biofunctionalization of nanoparticle assisted mass spectrometry as biosensors for rapid detection of plant associated bacteria, Biosensors and Bioelectronics, 2012, May, 35, 235-242. (IF5.602, 1/26, 3.85%, Electrochemistry, 4/73, 5.48%, Chemistry, Analytical, Times cited 1).

 

4.  Judy Gopal, Chia-Hsun Lee, Hui-Fen Wu*, Rapid and direct detection of invivo kinetics of pathogenic bacterial infection from mouse blood and urine. Journal of Proteomics, 2012, June, 75, 2972-2982 (IF5.074, 10/71, 14.08%, Biochemical Research Methods).

 

5.      Suresh Kailasa, Hui-Fen Wu*, Functionalized quantum dots modified with dopamine dithiocarbamate as the matrix for quantification of efavirenz in human plasma and as affinity probes for rapid identification of microwave tryptic digested proteins in MALDI-TOF-MS. Journal of Proteomics, 2012, June, 75, 2924-2933 (IF5.074, Times cited 1).

6.      Hui-Fen Wu*, Judy Gopal, Hani Abdelhamid, Nazim Hasan, Quantum dot applications endowing novelty to analytical proteomics, Proteomics, 2012, Oct, 12, 2949-2961. (IF4.505, 14/72, 19.44%, Biochemical research methods). Invited review article.

 

7.      Hani Abdelhamid, Hui-Fen Wu*, A method to detect metal-drug complexes and their interactions with pathogenic bacteria via graphene nanosheet assist laser desorption/ionization mass spectrometry and biosensors. Analytica Chimica Acta, 2012, 751, 94-104 (IF 4.555, 5/73, 6.85%).

 

8.      Hui-Fen Wu*, Judy Gopal, Muthu Manikandan, Future perspective of Nanoparticle interaction laser desorption/ionization mass spectrometry (NPILDI-MS) for rapid, simple, direct and sensitive detection of microorganisms. Journal of Mass Spectrometry, Special feature article-Perspective/Front cover image/Author Biographies (特寫文章/封面報導/人物介紹), 2012, Mar, 47, 355-363. (IF3.289, 7/41, 17.07%, Spectroscopy).

 

9.      Judy Gopal, Hui-Fen Wu*, Chia Hsun Lee, Muthu Manikandan, Tracing the pathogen staphylococcus aureus on laboratory ants using physical preconcentration coupled ZnO nanoparticle assisted MALDI-TOF MS. Analyst, 2012, Jan, 137 (2), 357-364 (Featured in the back cover image底頁封面報導) (IF4.23, 8/73, 10.96%).

 

10.  Kamlesh Shrivas, Hui-Fen Wu*, Rapid and highly sensitive protein extraction via cobalt oxide nanoparticle based liquid-liquid microextraction coupled with MALDI mass spectrometry, Analyst, 2012, Feb, 137 (4), 890-895 (IF4.23, 8/73, 10.96%). (Featured in the inside front cover image內頁封面報導)

 

11.  Suresh Kailasa, Hui-Fen Wu*, Dispersive liquid-liquid microextraction using functionalized Mg(OH)2 NPs with oleic acid as hydrophobic affinity probes for the analysis of hydrophobic proteins in bacteria by MALDI-MS, Analyst, 2012, 137 (19), 4490-4496 (IF4.23, 8/73, 10.96%).

 

12.  Muthu Manikandan, Nazim Hasan, Hui-Fen Wu*, Rapid and direct detection of attomole adenosine triphosphate (ATP) by MALDI MS using rutile titania chips. Analyst, 2012, 137 (21), 5128-5134. (IF4.23, 8/73, 10.96%).

 

13.  Suresh Kailasa, Hui-Fen Wu*, One-pot synthesis of dopamine dithiocarbamate functionalized gold nanoparticles for quantitative analysis of small molecules and phosphopeptides in SALDI and MALDI-MS. Analyst, 2012, April, 137 (7), 1629-1638. (IF4.23, 8/73, 10.96%, Times cited 2).

 

14.  Jayaram Narayana, Judy Gopal, Hui-Fen Wu*, Wound infection kinetics probed by MALDI-MS: Rapid profiling of Staphylococcus aureus in mice. Analyst, 2012, July, 137 (14), 3372-3380.

 

15.  Faheem Ahmad, Judy Gopal, Hui-Fen Wu*, Rapid and highly sensitive detection of single nematode via direct MALDI Mass Spectrometry. Talanta, 2012, May, 93, 182-185. (IF3.794, 12/73, 16.44%, Chemistry, Analytical, Times cited 1).

 

16.  Suresh Kailasa, Nazim Hasan, Hui-Fen Wu*, Identification of multiply charged proteins and amino acid clusters by liquid nitrogen assisted spray ionization mass spectrometry, Talanta, 2012, Aug, 97, 539-549. (IF3.794, 12/73, 16.44%, Chemistry, Analytical).

 

17.  Faheem Ahmad, Hui-Fen Wu*, High resolution detection of bacterial proteins using the Tris-EDTA buffer approach on MALDI-TOF mass spectrometry, Microchimica Acta, 2012, Feb, 176, 311-316. (IF3.033, 18/73, 24.66%, Chemistry, Analytical).

 

18.  Suresh Kailasa, Hui-Fen Wu*, Rapid enrichment of phosphopeptides by BaTiO3 nanoparticles after microwave-assisted tryptic digest of phosphoproteins, and their identification by MALDI-MS. Microchimica Acta, 2012, Oct, 179, 83-90. (IF3.033).

 

19.  Gangaraju Gedda, Judy Gopal, Hui-Fen Wu*, ESI-MS and MALDI-MS analysis of extrapolysaccharides of E.coli. Rapid Communications in Mass Spectrometry. 2012, July, 26, 1609-1616. (IF2.79, 13/42, 30.95%, Spectroscopy).

 

20.  Hui-Fen Wu*, Biochips and tissue chips – integrating biologists, physicist, chemist and material scientists, Joirnal of Biochips & Tissue Chips. Editorial Article. Vol.2, 1st Issue, 2012.

 

2011

 

1.         Judy Gopal, Jayaram Narayana, Hui-Fen Wu*, TiO2 nanoparticle assisted Mass spectrometry as biosensor of Staphylococcus aureus, key pathogen in nosocomial infections from air, skin surface and human nasal passage. Biosensors and Bioelectronics, 2011, Sep, 27, 201-206 (Times cited 6).

 

2.     Judy Gopal, Hui-Fen Wu*, Gangaraju Gedda, Quantifying the degradation of extracellular polysaccharides of Escherichia coli by CdS quantum dots. Journal of Materials Chemistry, 2011, 21, 13445-13451 (IF6.101, 16/225, 7.11%, Materials Science, Multidisciplinary, Times cited 3).

 

3.         Nazim Hasan, Judy Gopal, Hui-Fen Wu*, Rapid, sensitive and direct analysis of exopolysaccharides from biofilm on aluminum surfaces exposed to sea water using MALDI-TOF MS. Journal of mass spectrometry, 2011, 46, 1160-1167 (IF3.289, 8/42, 19.05%, Spectroscopy).

 

4.     Judy Gopal, Hui-Fen Wu*, Chia-Hsun Lee, The bifunctional role of Ag nanoparticles on bacteria- a MALDI-MS perspective. Analyst, 2011, Nov, 136, 5077-5083 (Times cited 2).

 

5.     Faheem Ahmad, Hui-Fen Wu*, Pt nanoparticles prepared in ionic liquid to extract bacteria from plasma via single drop microextraction coupled with MALDI mass spectrometry. Analyst, 2011, Oct, 136, 4020-4027 (Times cited 4).

 

6.     Kamlesh Shrivas, Kavita Agrawal, Hui-Fen Wu*, Application of platinum nanoparticles as affinity probe and matrix for direct analysis of small biomolecules and microwave digested proteins using matrix-assisted laser desorption/ionization mass spectrometry, Analyst, 2011, July, 136, 2852-2857. (Times cited 2)

 

7.     Nazim Hasan, Hui-Fen Wu*, Highly selective and sensitive enrichment of phosphopeptides via NiO nanoparticles using microwave assisted centrifugation-on particles ionization/enrichment approach in MALDI-MS. Analytical and Bioanalytical Chemistry, 2011, July, 400, 3451-3462. (IF3.841, 9/73, 12.33%, Chemistry, Analytical, Times cited 2).

 

8.     Hui-Fen Wu*, Feng-Tsai Chung, 3-Mercaptopropionic acid modified ZnSe quantum dots as the matrix for direct SALDI-MS analysis of peptides/proteins from high salt solution, Rapid Communications in Mass Spectrometry, 2011, June, 25, 1779-1786.

 

9.     Hui-Fen Wu*, Suresh Kailasa, Chi-Hsien Lin, Single drop microextraction coupled with MALDI mass spectrometry for rapid and direct analysis of hydrophobic peptides from biological samples in high salt solution, Rapid Communications in Mass Spectrometry, 2011, Jan, 25, 307-315.

 

10.    Suresh Kailasa, Hui-Fen Wu*, Semiconductor cadmium sulphide nanoparticles as matrices for peptides and as co-matrices for the analysis of large proteins in MALDI reflectron and linear TOF MS, Rapid Communications in Mass Spectrometry, 2011, Jan, 25, 271-280.

 

11.    Hui-Fen Wu*, Chen-Che Chin, Bo-Min Liu, Yuan-Chin Chen, Chi-Hsien Lin, Kai-Di Chang, Yi-Hsien Lee, Self assembly formation of magic ion of (H2O)20O+: observation of nanoscale cages of oxygenated water clusters induced from iron nanoparticles, Rapid Communications in Mass Spectrometry, 2011, Feb, 25, 410-414.

 

12.    Anita Ethiraj, Hui-Fen Wu*, Judy Gopal, Synthesis and characterization of ultrasmall thioglycerol modified ZnS quantum dots, Journal of the Chinese Chemical Society, 2011, 58, 805-812 (IF 0.718, 99/147, 67.35%, Chemistry, Multidisciplinary)

     

2010

 

1.         Judy Gopal, Hui-Fen Wu*, Yi-Hsien Lee, Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry as a rapid and reliable technique for directly evaluating bactericidal activity: Probing the critical concentration of ZnO nanoparticles as affinity probes. Analytical Chemistry, 2010, Dec, 82, 9617-9621. (IF5.856, 3/73, 4.11%, Times cited 10).

2.     Kamlesh Shrivas, Hui-Fen Wu*, Multifunctional nanoparticles composite for MALDI-MS: Cd2+ doped carbon nanotubes with CdS nanoparticles as the matrix, preconcentrating and accelerating probes of microwave enzymatic digestion of peptides and proteins for direct MALDI-MS analysis. Journal of Mass Spectrometry, 2010, Dec, 45, 1452-1460.(Times cited 2).

3.     Hui-Fen Wu*, Kavita Agrawal, Kamlesh Shrivas, Yi-Hsien Lee, On particle ionization/enrichment of multifunctional nanoprobes: washing/separation-free, acceleration and enrichment of microwave-assisted tryptic digestion of proteins via bare TiO2 nanoparticles in ESI-MS and comparing to MALDI-MS, Journal of Mass Spectrometry, 2010, Dec, 45, 1402-1408 (Times cited 2).

4.     Suresh Kailasa, Hui-Fen Wu*, Surface modified silver selinide nanoparticles as extrating probes to improve peptide/protein detection via nanoparticles-based liquid phase microextraction coupled with MALDI mass spectrometry. Talanta, 2010, Dec, 83, 527-534. (Times cited 2).

5.     Yaotang Ke, Suresh Kailasa, Hui-Fen Wu*, Zhen-Yu Chen, High resolution detection of proteins up to 80000 Da via multifunctional CdS quantum dots in laser desorption/ionization mass spectrometry. Talanta, 2010, Nov, 83, 178-184.(Times cited 6). Recommanded by Faculty 1000 Biology (F1000-Biology推薦論文).

6.     Hui-Fen Wu*, Suresh Kailasa, Lokesh Shastri, Electrostatically self -assembled –azides on zinc sulfide nanoparticles as multifunctional nanoprobes for peptide and protein analysis in MALDI-TOF MS, Talanta, 2010, July, 82, 540-547 (Times cited 1).

7.     Lokesh Shastri, Suresh Kailasa, Hui-Fen Wu*, Nanoparticle-single drop microextraction as multifunctional and sensitive nanoprobes: Binary matrix approach for gold nanoparticles modified with (4-mercaptophenyliminomethyl)-2-methoxyphenol for peptide and protein analysis in MALDI-TOF MS, Talanta, 2010, June, 81, 1176-1182 (Times cited 8).

8.     Li, Shuping; Guo, Zhongxian*; Wu, Hui-Fen*; Liu, Ying; Yang, Zhaoguang; Woo, Chee Hoe, Rapid analysis of Gram-positive bacteria in water via membrane filtration coupled with nanoprobe based MALDI-MS, Analytical and Bioanalytical Chemistry, 2010, July, 397, 2465-2476 (Times cited 9).

9.     Nazim Hasan, Hui-Fen Wu*, Yi-Hsien Li, Mohd Nawaz, Two step on particle ionization/enrichment via a washing and separation free approach: multifunctional TiO2 nanoparticles as desalting, accelerating and affinity probes for microwave assisted tryptic digestion of phosphoproteins in ESI-MS and MALDI-MS: comparison with microscale TiO2, Analytical and Bioanalytical Chemistry, 2010, Apr, 396, 2919-2929 (Times cited 7). (Selected as “Paper in forefront”前瞻論文).

10.    Suresh Kailasa, Hui-Fen Wu*, Multifunctional ZrO2 nanoparticles and ZrO2@SiO2 nanorods for improved MALDI-MS analysis of cyclodextrin, peptide and phosphoprotein. Analytical and Bioanalytical Chemistry, 2010, Feb, 396, 1115-1125 (Times cited 8).

11.    Suresh Kailasa and Hui-Fen Wu*, Interference free detection for small molecules: Probing the Mn2+-doped effect and cysteine capped effect on the ZnS nanoparticles for coccidiostats and peptide analysis in SALDI-TOF MS, Analyst, 2010, Mar, 135, 1115-1123 (Times cited 5).

12.    Abdul Bhat, Hui-Fen Wu*, Synthesis, characterization and application of modified Pd nanoparticles as preconcentration probes for selective enrichment/analysis of proteins via hydrophobic interactions from real world samples using Nanoparticle-Liquid-Liquid Microextraction coupled to MALDI-TOF MS. Rapid Communications in Mass Spectrometry, 2010, Dec, 24, 3547-3552 (IF2.79, Times cited:1).

13.    Yaotang Ke, Suresh Kailasa, Hui-Fen Wu*, Mohd Nawaz, Surface modified TiO2 nanoparticles as affinity probes and as matrices for the rapid analysis of phosphopeptides and proteins in MALDI-TOF-MS, Journal of separation science, 2010, Nov, 33, 3400-3408 (IF 2.733, Times cited:2).

 

 

2009

 

1.     Kamlesh Shrivas, Suresh Kailasa, Hui-Fen Wu*, Quantum dots laser desorption/ionization mass spectrometry (QDLDI-MS): multifunctional CdSe quantum dots as the matrix, concentrating probes and acceleration for microwave enzymatic digestion for peptide analysis and high resolution detection of proteins in a linear MALDI-TOF MS, Proteomics, 2009, May, 9, 2656-2667. (IF4.815, 13/71, 18.31%, Biochemical research methods, Times cited 33, Featured in the front cover image,封面報導).

2.     Kamlesh Shrivas, Suresh Kailasa, Hui-Fen Wu*, Quantum dots - electrospray ionization mass spectrometry: 3-mercaptopropanic acid capped CdS quantum dots as accelerating and enrichment probes for microwave tryptic digestion of proteins. Rapid Communications in Mass Spectrometry, 2009, 23, 3603-3607.

3.         Lokesh Shastri, Suresh Kailasa, Hui-Fen Wu*, Cysteine-capped ZnSe quantum dots as affinity and accelerating probes for microwave enzymatic digestion of proteins via direct matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis. Rapid Communications in Mass Spectrometry, 2009, Aug, 23, 2247-2252. (Times cited 11).

4.     Yuan-Chin Chen, Hui-Fen Wu*, Revolving hollow fiber-liquid phase microextraction coupled to GC/MS using electron ionization for quantification of five aromatic hydrocarbon isomers, Journal of Separation Science, 2009, Sep, 32, 3013-3019. (Times cited 5, Top 10 articles in BioMedLib).

5.     N. Rahman*, S.N.H. Azmi, Hui-Fen Wu, Nanoparticles and atmospheric pressure-matrix assisted laser desorption/ionization mass spectrometry for peptides and drugs analysis, The Icfai University press Journal of Chemistry, 2009, 2, 7-17.

 

2008

 

1.     Suresh Kailasa, Kamtaman Kiran, Hui-Fen Wu*, Comparison of ZnS Semiconductor Nanoparticles Capped with Various Functional Groups as the Matrix and Affinity Probes for Rapid Analysis of Cyclodextrins and Proteins in the SALDI-TOF Mass Spectrometry, Analytical Chemistry, 2008, Dec, 80, 9681-9688.(Times cited 44).

2.     Kamlesh Shrivas, Hui-Fen Wu*, Modified Silver Nanoparticle as Hydrophobic Affinity Probes for Rapid Analysis of Peptide and Proteins in Biological Samples by coupling liquid-liquid microextraction with AP-MALDI/ion trap and MALDI/Time of Flight Mass Spectrometry. Analytical Chemistry, 2008, Apr, 80, 2583-2589.(Times cited 49, Top 10 articles in BioMedLib).

3.     Kamlesh Shrivas, Hui-Fen Wu*, Oxidized multiwall carbon nanotubes for quantitative determination of cationic surfactants in water samples using AP-MALDI-ion trap Mass Spectrometry. Analytica Chimica Acta, 2008, Nov, 628, 198-203. (IF4.555, 5/73, 6.85%, Times cited 13).

4.     Kamlesh Shrivas, Hui-Fen Wu*, Applications of silver nanoparticles capped with different functional groups as the matrix and affinity probes in SALDI-TOF and AP-MALDI- ion trap mass spectrometry for rapid analysis of sulphur drugs and biothiols in human urine, Rapid Communications in Mass Spectrometry, 2008, Sep, 22, 2863-2872.(Times cited 32).

5.     Putty Sudhir, Kamlesh Shrivas, Zi-Chong Zhou, Hui-Fen Wu*, Single drop microextraction using silver nanoparticles as electrostatic probes for peptide analysis in AP-MALDI/MS and comparison with gold electrostatic probes and silver hydrophobic probes, Rapid Communications in Mass Spectrometry, 2008, Oct, 22, 3076-3086. (Times cited 15, Top 10 articles in BioMedLib).

6.     Kavita Agrawal, Hui-Fen Wu*, Bare silica nanoparticles as concentrating and affinity probes for rapid analysis of aminothiols, lysozyme and peptide mixtures using AP-MALDI/ion trap and MALDI/TOF mass spectrometry, Rapid Communications in Mass Spectrometry, 2008, Feb, 22, 283-290. (Times cited 28).

7.     Kavita Agrawal, Hui-Fen Wu*, Kamlesh Shrivas, Reverse Micelle-Microextraction as concentrating and affinity probes for rapid analysis of thiopeptide in the AP-MALDI/ion trap and MALDI/TOF Mass Spectrometry. Rapid Communications in Mass Spectrometry, 2008, May, 22, 1437-1444. (Times cited 7).

8.     Kamlesh Shrivas, Hui-Fen Wu*, Functionalized multiwalled carbon nanotubes as a preconcentrating probe for rapid monitoring of cationic dyestuffs in environmental water using AP-MALDI/MS. Journal of Separation Science, 2008, 31, 3603-3611.

9.     Chih-Hao Yang, Nadeem Khan, Hui-Fen Wu*, Differentiation and quantification of xylene isomers by combining headspace solid-phase microextraction/gas chromatography and self-ion molecule reaction in an ion trap tandem mass spectrometry, Journal of Separation Science, 2008, Sep, 31, 3050-3057. (IF2.733, Times cited 3).

10.    Hui-Fen Wu*, Hsin-Yi Ku, Jyh-Hao Yen, Liquid-phase microextraction for rapid AP-MALDI and quantitation of nortriptyline in biological matrices, Journal of Separation Science, 2008, July, 31, 2288-2294.(IF2.733, Times cited 12, Top 10 articles in BioMedLib).

11.    Hui-Fen Wu*, Jyh-Hao Yen, Dynamic liquid phase nanoextraction coupled to GC/MS for rapid analysis of methoxyacetophenone and anisaldehye isomers in urine. Journal of Separation Science, 2008, July, 31, 2295-2302. (IF2.733, Top 10 articles in BioMedLib, Times cited 2).

12.    Kamlesh Shrivas, Hui-Fen Wu*, Ultrasonication followed by single drop microextraction combined with GC/MS for rapid determination of organochlorine pesticides from fish. Journal of Separation Science, 2008, Feb, 31, 380-386. (Times cited 20).

13.    Yao-Tang Ke, Hui-Fen Wu*, Applications of functional nanoparticles as the affinity probes for analysis of peptides and proteins by coupling solvent microextraction with the MALDI mass spectrometry, Chemistry (the Chin. Chem. Soc., Taipei), 2008, 66, No3, 231-240.

 

2007

 

1.         Kamlesh Shrivas, Hui-Fen Wu*, Quantitative bioanalysis of quinine by AP-MALDI/MS assisted with dynamic drop-to-drop solvent microextraction, Analytica Chimica Acta, 2007, Dec, 605, 153-158. (IF4.555, 5/73, 6.85%, Times cited 18).

2.     Bih-Show Lou, Yuan-Chin Chen, Hui-Fen Wu*, Probing the non-covalent binding interaction of Na+ channel inactivation gate peptide in linker between domain III and IV with 5,5-diphenyhydantoin drug in Electrospray/Ion Trap Tandem Mass Spectrometry, Rapid Communications in Mass Spectrometry, 2007, Dec, 21, 2795-3802.

3.     Kamlesh Shrivas, Hui-Fen Wu*, Rapid determination of caffeine in one drop of beverages and foods using drop to drop solvent microextraction with gas chromatography/mass spectrometry, Journal of Chromatography A, 2007, Nov, 1170, 9-14. (IF4.531, 6/73, 8.22%, Times cited 27).

4.     Kavita Agrawal, Hui-Fen Wu*, Drop-to-drop solvent microextraction coupled with gas chromatography mass spectrometry for rapid determination of trimeprazine in urine and blood of rats: application to pharmacokinetic studies. Rapid Communications in Mass Spectrometry, 2007, Oct, 21, 3352-3356. Times cited 13.

5.     Shuchen Hsieh*, Hsin-Yi Ku, Yao-Tang Ke, Hui-Fen Wu*, Self-Assembled Monolayer Modified Silicon Substrate to enhance the sensitivity of peptide detection for AP-MALDI Mass Spectrometry. Journal of Mass Spectrometry, 2007, Dec, 42, 1628-1636. (Times cited 11).

6.     Kamlesh Shrivas, Hui-Fen Wu*, A Rapid, Sensitive and Effective Quantitative Method for Simultaneous Determination of Cationic Surfactant mixtures from River and Municipal Waste Water by Direct Combination of Single Drop Microextraction with AP-MALDI Mass Spectrometry Journal of Mass Spectrometry, 2007, Dec, 42, 1637-1644. (Times cited 18).

7.     Kamlesh Shrivas, Hui-Fen Wu*, Single drop microextraction as a concentrating probe for rapid screening of low molecular weight of drugs from human urine using AP-MALDI Mass Spectrometry. Rapid Communications in Mass Spectrometry, 2007, Sep, 21, 3103-3108. (Times cited 26).

 

2006

 

1.         Ramaiyan Sekar, Hui-Fen Wu*. Quantification method for analysis of monensin in soil, water and urine by direct combining single drop microextraction with atmospheric pressure matrix assisted laser desorption/ionization mass spectrometry. Analytical Chemistry, 2006, Sep, 78, 6306-6313. (Times cited 26).

2.         Hui-Fen Wu*, Jih-Hao Yen, Chen-Che Chin, Combining drop to drop solvent microextraction (DDSME) with gas chromatography/mass spectrometry using electronic ionization and self-ion/molecule reaction method to determine methoxyacetophenone isomers in one drop of water. Analytical Chemistry, 2006, 78, 1707-1712. (Times cited 31).

3.     Hui-Fen Wu*, Chi-Hsien Lin. Direct combination of immersed single-drop microextraction with atmospheric pressure matrix-assisted laser desorption/ionization tandem mass spectrometry for rapid analysis of a hydrophilic drug via hydrogen-bonding interaction and comparison with liquid-liquid extraction and liquid-phase microextraction using a dual gauge microsyringe with a hollow fiber. Rapid Communications in Mass Spectrometry, 2006, Aug, 20, 2511-2515. (Times cited 20).

4.         Bin-Wei Lai, Bo-Ming Liu, Pradip Malik, Hui-Fen Wu*, Combination of Liquid-Phase Hollow Fiber Membrane Microextraction with Gas Chromatography/Negative Chemical Ionization Mass Spectrometry for the Determination of Dichlorophenol Isomers. Analytica Chimica Acta. 2006, Aug, 576, 61-66. (Times cited 20).

5.         N. Rahman*, S.N.H. Azmi, H. F. Wu, The importance of impurity analysis in pharmaceutical products: an integrated approach, Accreditation and Quality Assurance, Springer Verlag, 2006, 11, 69-74.

 

 

2005

 

P. Sudhir, H.-F. Wu*, Z. C. Zhou, identification of peptides using gold nanoparticles-assisted single drop microextraction coupled with AP-MALDI mass spectrometry. Analytical Chemistry, 2005, 77, 7380-7385.

 

P. Sudhir, H.-F. Wu*, Z. C. Zhou, An application of electrospray ionization tandem mass spectrometry to probe the interaction of Ca+2/Mg+2/Zn+2 and Cl- with gramicidin A, Rapid Communications in Mass Spectrometry, 2005, 19, 1517-1521.

 

P. Sudhir, H.-F. Wu*, Z. C. Zhou, Probing the interaction of kojic acid antibiotics with iron (III) chloride by using electrospray tandem mass spectrometry, Rapid Communications in Mass Spectrometry, 2005, 19, 209-212.

 

H. F. Wu*, Developing chemical ionization, host-guest chemistry, self- ion/molecule reaction, single drop microextraction and electrospray mass spectrometry in an ion trap mass spectrometry, Chemistry (the Chin. Chem. Soc., Taipei). 2004, 62, 443-450.

 

C. H. Yan, H. F. Wu*, A Liquid-Phase Microextraction Method, combining a Dual Gauge Microsyringe with a Hollow Fiber Membrane for the determination of Organochlorine Pesticides in Water by Gas Chromatography/Ion Trap Mass Spectrometry.Rapid Communications in Mass Spectrometry, 2004/12, 18, 3015-3018.

 

N. Khan, H.-F. Wu*, Analysis of silymarin extracted from commercial dosage forms by combining liquid-liquid extraction with negative electrospray tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 2004/12, 18, 2960-2962.

 

B. M. Liu, P. Malik, H. F. Wu*, Single-Drop Microextraction and Gas Chromatography-Mass Spectrometric Determination of Anisaldehyde Isomers in Human Urine and Blood Serum. Rapid Communications in Mass Spectrometry, 2004/9, 18, 2059-2064.

 

H. F. Wu*, P. Y. Lin, Ethylenediamine as a liquid reagent to probe the hydrogen - bonding and host guest interaction with crown ethers in an Ion Trap Tandem Mass Spectrometer, Rapid Communications in Mass Spectrometry, 2004/6, 18, 1365-1373.

 

H. F. Wu*, C. H. Chen, M. T. Wu, Observation of Self - Ion - Molecule Reaction during collisionally activated dissociation in an ion - trap mass spectrometer, Journal of Mass Spectrometry, 2004/4, 39, 396-401.

 

L. Brewer*, K. Krushwitz, R. Lamoreaux, H.F. Wu, Properties of valuable new intermetallics: Brewer–Engel model applied to the bonding of transition metal dialuminides, Intermetallics, 2003/11, 1103-1109.

 

H. F.Wu*, W. F. Wu, Comparing differentiation of xylene isomers by electronic ionization, chemical ionization and Self-Ion/Molecule Reactions and the first observation of methyne addition ions for xylene isomers in Self-Ion/Molecule Reactions for non-nitrogenated compounds, Rapid Communications in Mass Spectrometry, 2003/11, 17, 2399- 2406.

 

H. F. Wu*, C. H. Chen, L. C. Lu, Probing the Reaction Mechanisms of Self - Ion/Molecule Reaction for Dopamine in an Ion Trap Mass Spectrometer, Rapid Communications in Mass Spectrometry, 2003/5, 17, 1479-1482.

 

H. F. Wu*, P. Y. Lin, Probing the Effects of Reagent Gas Pressure and Ion Source Temperature for Dimethyl Ether Chemical Ionization of Tricyclic Antidepressants in an External Source Ion Trap Mass Spectrometer, J. Chin. Chem. Soc., 2003/12, 50, 1251-1257.

 

H. F. Wu*, Y. J. Chuan, Isomer Differentiation by Combining Gas Chromatography, Selective Self–Ion/ Molecule Reaction and Tandem Mass Spectrometry in an Ion Trap Mass Spectrometer, Rapid Communications in Mass Spectrometry, 2003, 17,1030-1036.

 

H. F. Wu*, Y. R. Chen, B. W. Lai, Novel observation of total ion chromatogram splitting under positive chemical ionization in an external source Ion Trap Mass Spectrometer, Journal of Mass Spectrometry, 2003, 38,458-459.

 

HF Wu*, LC Lu, 2002年諾貝爾化學獎-質譜儀分析技術的突破,開展生化科技新領域, 科學發展月刊, 2003, 361, 50-53.

 

H. F. Wu*, S. M. Huan, C. F. Wu, 2002, Conformational Analysis and Binding Affinity Determination for Host-Guest Complexation of Alkali Metal Ion with Bis (Crown Ether)s by Electrospray Mass Spectrometry and Molecular Modeling, European Journal of Mass Spectrometry, 8, 375-380.

 

H. F. Wu*, C. H. Chen, 2002, Hydroxide and oxygen atom attachment to dichlorophthalic anhydride in negative ion chemical ionization with collisionally activated dissociation in an external source ion trap mass spectrometer, European Journal of Mass Spectrometry, 8, 329-332.

 

Hui-Fen Wu*, Li-Wei Chen and Chien-Hung Chen, 2001/11, Probing the Reactive Sites for Ion/Molecule Reactions of Anthraquinones with Dimethyl Ether by an External Source Ion Trap Tandem Mass Spectrometer and Computational Chemistry, Rapid Communications in Mass Spectrometry, 15, 1977-1987.

 

Hui-Fen Wu* and Ming-Yi Ho, 2001, Selective Self - Ion / Molecule Reactions in Both External and Internal Source Ion Trap Mass Spectrometers, Rapid Communications in Mass Spectrometry, 15, 1309-1316.

 

Hui-Fen Wu*, Chien-Hung Chen and Ming-Yi Ho, 2001, April,“Examination of the Best Pressure Range for Ion/Molecule Reactions of Anthraquinones in an External Source Ion Trap Mass Spectrometer” Analytical Sciences, 17, 515-518.

 

Hui-Fen Wu*, Li-Wei Chen, Jhen-Chen Wang and Ya-Ping Lin, 2001, February,“Simulation of the Collisional Cooling Effect for Binary and Ternary Buffer Gas Mixtures in a Quadrupole Ion Trap Mass Spectrometer”. European Journal of Mass Spectrometry, 7, 1-6.

 

Hui-Fen Wu*, 2000, August, “Study of Temperature and Pressure Effect of Negative Chemical Ionization Mass Spectrometry Using Methane and Oxygen as Reagent Gases in an External Source Ion Trap Mass Spectrometer”, Journal of Mass Spectrometry, 35, 1049-1050.

 

Hui-Fen Wu* and Ya-Ping Lin, 2000, June, “Study of Ion-Molecule Reactions and Collisionally Activated Dissociation of Dopamine and Adrenaline by an Ion Trap Mass Spectrometer with an External Ionization Source. European Journal of Mass Spectrometry, 6, 65-77.

 

Hui-Fen Wu*, Li-Wei Chen and Ya-Ping Lin, 1999, December, “Simulation of Collisional Cooling Effect in a Quadrupole Ion Trap Mass Spectrometer”. Journal of the Chinese Chemical Society, 46, 923-932.

 

Hui-Fen Wu* and Ya-Ping Lin, 1999, December, “Determination of Sensitivity of the External Source Ion Trap Tandem Mass Spectrometer Using Dimethyl Ether Chemical Ionization”. Journal of Mass Spectrometry, 34, 1283-1285.

 

Hui-Fen Wu*and Li-Wei Chen, 1998, October, “Study of Host-Guest Complexation of Alkaline Ion, Aluminum Ion and Transition Metal Ions with Crown Ethers by Fast Atom Bombardment Mass Spectrometry”. Journal of the Chinese Chemical Society, 45, 689-699.

 

L. Brewer* and H.- F. Wu,1997, “Parameters for Calculation of Properties of Acid-Base Intermetallics”. Proc.-Electrochem. Soc., Volume: 97-39, number: High Temperature Materials Chemistry, p 60-69, (CA:128(7)80209z).

 

Hui-Fen Wu, Leo Brewer*, 1997, January, “Calculation of Thermodynamic Effect of the Brewer-Engel Generalized Acid - Base Reactions of the 1:1 Intermetallics for Nontransition Metals Al, Mg with Transition Metals”. Journal of Alloys and Compounds, 247,1-8.

 

E.J. Alvarez, H.-F. Wu, C.-C. Liou and J. S. Brodbelt*, 1996, September, “Collisionally Activated Dissociation of Transition Metal Ion/Polyether Complexes in a Quadrupole Ion Trap”. Journal of the American Chemical Society, 118, 9131-9138.

 

Hui-Fen Wu, Leo Brewer*, 1996, February, “Calculation of Binary Phase Diagrams of Refractory Metals Ta, W, Tc and Re with Liquid Metals Am, Cm, and Bk by Using a Modification of Regular Solution Theory”. Journal of Phase Equilibria, 17,36-39.

 

C.-C.Liou, J. Isbell. H.-F. Wu. J. S. Brodbelt*, R. A. Bartsch, J. C. Lee and J. L. Hallman, 1995, April, “Structually- Selective Gas-Phase Ion-Molecule Reactions of Dibenzo-16-Crown-5 Compounds” Journal of Mass Spectrometry, 30,572-580.

 

H.-F. Wu, J. S. Brodbelt*, 1995, February , “Gas-Phase Chelation Reactions of Monopositive Cations with Heteroaromatic Ligands”. Inorganic Chemistry, 34, 615 –621.

 

H.-F. Wu, J. S. Brodbelt*, 1994, October, “Influence of Heteroatom Donors on the Orders of Relative Gas-Phase Binding Affinities of Macrocyclic Polyethers”. Journal of Inclusion Phenomena and Molecular Recognition in Chemistry , 18, 37-44.

 

H.-F. Wu, J. S. Brodbelt*, 1994, July, “The Gas-Phase Complexation of Monovalent Alkaline Earth Metal Ions with Polyethers: Comparision to Alkali Metal Ion and Aluminum Ion Complexation”. Journal of The American Chemical Society, 116,6418-6426.

 

C.-C .Liou, H.-F. Wu , J. S. Brodbelt*, 1994, April, “Hydrogen-Bonding Interactions in Gas-Phase Polyether/Ammonium Ion-Complexes”. Journal of The American Society for Mass Spectrometry, 5, 260-273.

 

H.-F. Wu, J. S. Brodbelt*, 1993, September, “Comparison of the Orders of Gas-Phase Basicities and Ammonium Ion Affinities of Polyethers by the Kinetic Method and Ligand Exchange Technique.” Journal of The American Society for Mass Spectrometry, 4,718-722.

 

H.-F. Wu, J. S. Brodbelt*, 1993, April, “Effects of Reaction Ion Kinetic Energy on Both Endothermic and Exothermic Ion/Molecule Reactions in a Quadrupole Ion Trap Mass Spectrometer.” International Journal of Mass Spectrometry and Ion Processes, 124,175-184.

 

H.-F. Wu, J. S. Brodbelt*, 1992, Winter “Effects of Collisional Cooling on Ion Detection in a Quadrupole Ion Trap Mass Spectrometer”. ICR/Ion Trap Newsletter, 25,22-24.

 

H.-F. Wu, J. S. Brodbelt*,1992, May, “Effects of Collisional Cooling on Ion Detection in a Quadrupole Ion Trap Mass Spectrometer”. International Journal of Mass Spectrometry and Ion Processes, 115,67-81.

 

 

 

研討會論文/邀請演講:

 

lJudy Gopal, Nazim Hasan, H. F. Wu*, Fabrication of TiO2 nanoparticle thin film on titanium surfaces for application as bacterial sensor/biochip for rapid, sensitive and direct analysis of pathogenic bacteria using MALDI-MS, Nano 2012, International Conference & exhibition on nanotechnology & nanomedicine  Omics Group, March 12th-14th, Omaha, Nebraska. US. Oral presentation.

l M. Manikandan, Nazim Hasan, H. F. Wu*, Nanoparticle assisted enhanced biosynthesis of haloarchaeal caroteinoid pigments: Preconcentration of pigments through Pt nanoparticle based liquid liquid microextraction for MALDI-MS analysis. Nano 2012, International Conference & exhibition on nanotechnology & nanomedicine  Omics Group, March 12th-14th, Omaha, Nebraska. US. Oral presentation.

l  H. F. Wu*, Nanoparticle interaction laser desorption/ionization mass spectrometry for rapid, simple, direct and sensitive analysis of pathogenic bacteria, NSYSU & UCSD Symposium, May 19-23, 2012, 中山大學. Invited Speaker.

l  Hui-Fen Wu*, Annual Retreat of the Marine Biotechnology Degree Program, Jan 16, 2012, Invited Speaker.

l  H. F. Wu*, J. Gopal, C. H. Lee, Rapid and direct detection of invivo kinetics of pathogenic bacterial infection from mouse blood and urine. 2 屆分析蛋白質體年會.The second International Congress on Analytical Proteomics, Ourense, Spain. July 18-20, 2011. Invited Speaker and evaluation panel for bacteria/animal for the speech/poster awards.

l  Judy Gopal, Jayaram Narayan, Hui-Fen Wu*, TiO2 nanoparticle assisted mass spectrometry for affinity capture of Staphylococcus aureus, the predominant nosocomial pathogen from air, skin surface and human nasal passage. 2 屆亞洲及太平洋質譜會議.The 2th Asian and Oceanic Mass Spectrometry Conference. Aug. 17-19, 2011, Busan, Korea.

l  Chia-Hsun Lee, Judy Gopal, Hui-Fen Wu*, BCrO42- ionic liquid applied in bacterial analysis from fresh and spoilt yogurt.第十七屆分析技術交流研討會, May14-15, 2011.中興大學.

l  Hui-Fen Wu*,台俄開發蛋白質體學研究之新穎質譜法研討會, Probing the dual personality of ZnO and Ag nanoparticles in bacteria analysis in MALDI Mass Spectrometry, April 26, 2011, 中山大學. Invited Speaker.

l  Chia-Hsun Lee, Judy Gopal, Hui-Fen Wu*, Mass Spectrometry enabled by a novel Cr6+ containing ionic solution as biosensor of yogurt bacteria.第八屆台灣質譜年會暨學術研討會, July 10-12, 2011, Sinica.

l  Hui-Fen Wu*, Sample pretreatment free mass spectrometry based on nanomaterials,第六屆海峽兩岸分析化學會議.Sep. 9-10, 2010, Da-Lien, China. Invited Speaker.

l  Hui-Fen Wu*, Applications of multifucntional quantum dots and nanoparticle mass spectrometry,台灣質譜學會夏季專題研討會-奈米材料與質譜分析技術, Aug. 13, 2010, 交通大學. Invited Speaker.

l  Hui-Fen Wu*, Nanoprobe based mass spectrometry.第三屆世界華人質譜研討會, 2010730-81,吉林省長春市. Invited Speaker.

l  Hui-Fen Wu*, 1. Multifunctional nanomaterials for rapid protein and peptide analysis in MALDI, ESI and liquid nitrogen spray mass spectrometry 2. Nanoparticles in ionic liquid-single drop microextraction for highly sensitive and background free detection of bacteria from human plasma in MALDI-MS. 2010, July 27,台灣大學化學系演講.

l  Nazim Hasan, Hui-Fen Wu*, Yi-Hsien Li, Mohd Nawaz, Two step-on particle ionization/enrichment via washing and separation free approach: multifunctional TiO2 nanoparticles as desalting, accelerating and affinity probes for microwave-tryptic digestion of phosphoproteins in ESI and MALDI-MS: comparing to microscale TiO2, 7屆台灣質譜年會暨學術研討會, 2010, June 27-29, 高雄醫學大學.

l  Suresh Kumar Kailasa and Hui-Fen Wu*, Interference free detection for small molecules: Probing the Mn2+-doped effect and cysteine capped effect on the ZnS nanoparticles for coccidiostats and peptide analysis in SALDI-TOF MS, 7屆台灣質譜年會暨學術研討會, 2010, June 27-29,高雄醫學大學.

l  Lokesh Shastri, Suresh Kumar Kailasa, Hui-Fen Wu*, Nanoparticle-single drop microextraction as multifunctional and sensitive nanoprobes: Binary matrix approach for gold nanoparticles modified with (4-mercaptophenyliminomethyl)-2-methoxyphenol for peptide and protein analysis in MALDI-TOF MS7屆台灣質譜年會暨學術研討會, 2010, June 27-29, 高雄醫學大學.

l  Suresh K. Kailasa, Hui-Fen Wu*, Multifunctional ZrO2 nanoparticles and ZrO2@SiO2 nanorods for improved MALDI-MS analysis of cyclodextrin, peptide and phosphoprotein. 7屆台灣質譜年會暨學術研討會, 2010, June 27-29, 高雄醫學大學.

l  Hui-Fen Wu*, Multifunctional nanomaterials for rapid protein and peptide analysis in MALDI and ESI mass spectrometry.58 屆日本質譜年會暨第一屆亞太質譜年會.1st Asian and Oceanic Mass Spectrometry Conference, Japan. Tsukuba, 2010, June 16-18. Invited Speaker.

l  Suresh Kailasa, Hui-Fen Wu*, Improvement of signal intensities for protein analysis with cadmium sulphide nanomaterials as the matrix in MALDI-TOF-MS.58 屆日本質譜年會暨第一屆亞太質譜年會.1st Asian and Oceanic Mass Spectrometry Conference, Japan. Tsukuba, June 16-18, 2010.

l  Nazim Hasan, Hui-Fen Wu*, Highly selective and sensitive enrichment of phosphopeptides via NiO nanoparticles using microwave assisted centrifugation-on particles ionization/enrichment approach in MALDI-MS. 58 屆日本質譜年會暨第一屆亞太質譜年會.1st Asian and Oceanic Mass Spectrometry Conference, Japan. Tsukuba, June 16-18, 2010.

l  Yi-Hsien Lee, Nazim Hasan, Hui-Fen Wu*, Two-step on-particle ionization/enrichment via a washing- and separation-free approach for phosphopeptide analysis in ESI and MALDI-MS.第十六屆分析化學技術交流研討會, 2010, 515,16, 台灣大學化學系.

l    Hui-Fen Wu*, Multifunctional quantum dots and nanomaterials for rapid protein   and  peptide analysis in the MALI-MS, 98年中國化學會年會, 2009125, 6, 義守大學. Invited Speaker.

l   Nawaz, Mohd; Shastri, Lokesh; Wu, Hui-Fen*, Bifunctionalized capped Silver nanoparticle coupled Single Drop Microextraction as a high affinity probe for protein and biomolecules analysis in MALDI-TOF MS, 18th International Mass Spectrometry Conference, Aug. 30-Sep. 4, 2009, Bremen, Germany.

l  H. F. Wu*, S. Kailasa, S. Lokesh, Synthesis of Electrostatically Self Assembled Azide Stabilized ZnS Nanoparticles as Affinity Probes for Enrichment, Desalting and Rapid Analysis of Peptides and Proteins by direct MALDI-TOF MS. 18th International Mass Spectrometry Conference, Aug. 30-Sep. 4, 2009, Bremen, Germany.

l   Hasan, Nazim; Lee,Yi Hsieh; Mohd Nawaz; Wu, Hui-Fen*, Trifunctional TiO2 nanoparticles for acceleration,desalting and enrichment of microwave-digested proteins and phosphoproteins via ESI and MALDI-TOF mass spectrometry analysis. 18th International Mass Spectrometry Conference, Aug. 30-Sep. 4, 2009, Bremen, Germany.

l  Hui-Fen Wu*, Applications of multifunctional quantum dots and nanomaterials as the matrix, affinity probes, acceleration for microwave digestion, desalting approach, liquid phase microextraction probes and improved resolution for rapid protein and peptide analysis in the MALDI-MS.台灣質譜學會學術研討會暨2009質譜年會, 2009625-26,中興大學. Invited Speaker.

l  Kamlesh Shrivas, Suresh Kailasa, Hui-Fen Wu*, Quantum dots laser desorption/ionization MS: multifunctional CdSe quantum dots as the matrix, concentrating probes and acceleration for microwave enzymatic digestion for peptide analysis and high resolution detection of proteins in a linear MALDI-TOF MS. 台灣質譜學會學術研討會暨2009質譜年會, 2009625-26,中興大學.

l  Lokesh Shastri, Suresh Kailasa, Hi-Fen Wu*, Cysteine capped ZnSe quantum dots as affinity and accelerating probes of microwave enzymatic digestion for proteins via direct MALDI-TOF MS analysis. 台灣質譜學會學術研討會暨2009質譜年會, 2009625-26,中興大學.

l  Shu-Ray Kuo, Hui-Fen Wu*, 硫化鉛量子點輔助雷射脫附游離質譜法在蛋白質及小分子化合物的應用, 台灣質譜學會學術研討會暨2009質譜年會, 2009625-26,中興大學.

l  Hui-Fen Wu*, Multifunctional quantum dots and nanoparticles for rapid protein and peptide analysis in the matrix Assisted Laser Desorption/Ionization Mass Spectrometry. 2009, June 17, 清華大學化學系演講.

l  Shu-Ray Kuo, Hui-Fen Wu*, 功能性鉑奈米粒子在雷射脫附質譜法上的應用,分析化學技術交流研討會. 2009.

l  Hui-Fen Wu*, Functional Group Effects of ZnS Semiconductor Nanoparticles as the Matrix and Nanoprobes for Rapid Analysis of Biological Samples and Mushroom in MALDI-TOF Mass Spectrometry. 97年度中國化學會年會. 2008, 125 ~ 7,彰化師範大學. Invited Speaker.

l  Putty-Reddy Sudhir, Kamlesh Shrivas, Zi-Cong Zhou, Hui-Fen Wu*, Single drop microextraction using silver nanoparticles as electrostatic probes for peptide analysis in AP-MALDI/MS and comparison with gold electrostatic probes and silver hydrophobic probes, 2008 International Chemical Conference, Taipei: Analytical Chemistry. 2008, Oct.2-5,中山大學化學系.

l  Chih-Hao Yang, Nadeem Khan, Hui-Fen Wu*, Differentiation and quantification of xylene isomers by combining headspace solid-phase microextraction/gas chromatography and self-ion molecule reaction in an ion trap tandem mass spectrometry. 2008 International Chemical Conference, Taipei: Analytical Chemistry. 2008, Oct.2-5,中山大學化學系.

l  Kamlesh Shrivas, Hui-Fen Wu*, Applications of silver nanoparticles capped with different functional groups as the matrix and affinity probes in SALDI-TOF and AP-MALDI- ion trap mass spectrometry for rapid analysis of sulphur drugs and biothiols in human urine. 2008 International Chemical Conference, Taipei: Analytical Chemistry. 2008, Oct.2-5,中山大學化學系.

l  Kamlesh Shrivas, Hui-Fen Wu*, Functionalized multiwalled carbon nanotubes as a preconcentrating probe for rapid monitoring of cationic dyestuffs in environmental water using AP-MALDI/MS. 2008 International Chemical Conference, Taipei: Analytical Chemistry. 2008, Oct.2-5,中山大學化學系.

l  Hui-Fen Wu*, Kamlesh Shrivas, Single drop microextraction using silver nanoparticles as electrostatic probes for peptide analysis in AP-MALDI/MS and comparison with gold electrostatic probes and silver hydrophobic probes. HUPO 7th Annual World Congress 2008. Aug. 16-20, Amsterdam, Netherlands.

l  Hui-Fen Wu*, 2屆世界華人質譜研討會暨2008台灣質譜年會, 2008626-27, Sinica. Page 77-86.

l  Hui-Fen Wu*,  Modified Silver Nanoparticle as a hydrophobic affinity probe for analysis ofpPeptides and proteins by using MALDI Mass Spectrometry. 56th ASMS Conference On Mass Spectrometry and Allied Topics, Denver, Colorado, 2008, June 1 - 5.

l  Hui-Fen Wu*, Kamlesh Shrivas, Modified Silver Nanoparticle as a Hydrophobic Affinity Probe for Rapid Analysis of Peptide and Proteins in Biological Samples by using Liquid-Liquid Microextraction coupled to MALDI Mass Spectrometry,第五屆兩岸分析化學研討會暨第十四屆分析技術交流研討會, 2008524-25, 高雄醫學大學. Invited Speaker.

l  Hui-Fen Wu*, 1. Novel liquid phase microextraction techniques coupled to mass spectrometry for pharmacokinetic study, environmental and protein analysis 2. Application of nano-particles on mass spectrometry, 2008, Jan. 9,中山醫學大學化學系演講.

l  Hui-Fen Wu*, Hsin-Yi Ku, Jyh-Hao Yen, A liquid phase microextraction method using a micro pipette with disposable tips as a concentrating probe for rapid analysis and quantitative determination of nortriptyline drug from biological matrices in the AP-MALDI mass spectrometry, 96年中國化學會年會暨第十一屆台北國際化學會議, 2007, Dec.14-16, 清華大學化學系.

l  Shuchen Hsieh*, Hsin-Yi Ku, Yao-Tang Ke, Hui-Fen Wu*, Self-Assembled Monolayer Modified Silicon Substrate to enhance the sensitivity of peptide detection for AP-MALDI Mass Spectrometry. 96年中國化學會年會暨第十一屆台北國際化學會議, 2007, Dec.14-16, 清華大學化學系.

l  Hui-Fen Wu*, 1. Novel liquid phase microextraction techniques coupled to mass spectrometry for pharmacokinetic study, environmental and protein analysis 2. Application of nano-particles on mass spectrometry. 20071122.台灣大學化學系演講.

l  Yuan-Chin Chen, Hui-Fen Wu*, 大氣壓基質輔助雷射脫附質譜法結合一滴溶劑微量萃取技術直接對魚體組織作藥物的定量分析.第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Kavita, Feng-Tsain Chung, Hui-Fen Wu*, Atmospheric Pressure Matrix Assisted Laser Desorption/Ionization Mass Spectrometry with Micelle-Assisted Solvent Microextraction for Rapid Analysis of Thiopeptide. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Kamlesh Shrivas, Hui-Fen Wu*, A rapid, sensitive and effective quantitative method for simultaneous determination of cationic surfactant mixtures from river and municipal waste water by direct combination of single drop microextraction with AP-MALDI mass spectrometry. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Kamlesh Shrivas, Hui-Fen Wu*, Single Drop Microextraction as a Concentrating Probe for Rapid Screening of Low Molecular Weight Drugs from Human Urine. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Kamlesh Shrivas, Hui-Fen Wu*, Feng-Tsain Chung, A simple and rapid quantitative method by direct coupling drop-to-drop solvent microextraction with gas chromatography/mass spectrometry to determine caffeine in one drop of beverages and foods. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Kamlesh Shrivas, Yuan-Chin Chen, Hui-Fen Wu*, Rapid ultrasonic extraction followed single drop microextraction combined with gas chromatography -mass spectrometry to study organochlorine pesticides from fish. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Shuchen Hsieh, Hsin-Yi Ku, Yao-Tang Ke, Hui-Fen Wu*, 表面修飾自組裝薄膜矽基質提升大氣壓基質輔助雷射游離質譜儀上的胜肽鑑定靈敏度. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Hsin-Yi Ku, Hui-Fen Wu*, A rapid and quantitative method for analysis of traditional Chinese medicine by combining Microwave assisted extraction followed Ultrasonic assisted Drop to Drop Solvent Microextraction with a hollow fiber coupled with AP-MALDI tandem mass spectrometry to determine Evodia rutaecarpa in one drop of urine and plasma. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Hsin-Yi Ku, Hui-Fen Wu*, 微波萃取結合一滴溶劑一滴水樣之超微量萃取法連結大氣壓基質輔助雷射脫附質譜於中藥材黃蓮之定性定量分析. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  A desalting method using HostGuest complexation to probe the non-covalent binding interaction of Na+ channel inactivation gate peptide in linker between domain III and IV with phenytoin drug in Electrospray /Ion Trap Tandem Mass Spectrometry Spectrometry. 第四屆台灣質譜年會暨國際學術交流研討會, 2007629 ~ 30.成功大學.

l  Hui-Fen Wu*, Kamlesh Shrivas, Direct combination of Single Drop Microextraction with AP-MALDI Mass Spectrometry for rapid screening of low molecular weight of drugs from human urine and simultaneous determination of cationic surfactant mixtures from river and municipal waste water,13屆分析技術交流研討會, 2007, May 26, 27, 清華大學. Invited Speaker.

l  Bih-Show Lou, Yuan-Chin Chen, Hui-Fen Wu*, A desalting method using Host – Guest complexation to probe the non-covalent binding interaction of Na+ channel inactivation gate peptide in linker between domain III and IV with phenytoin drug in Electrospray / Ion Trap Tandem Mass Spectrometry.13屆分析技術交流研討會, 2007, May 26, 27, 清華大學.

l  Yuan-Chin Chen, Hui-Fen Wu*, 旋轉式中空纖維管液相微萃取法結合氣相層析質譜儀使用電子游離法及自身離子分子反應對異構物作定性定量分析.13屆分析技術交流研討會, 2007, May 26, 27, 清華大學.

l  謝淑貞, 古欣怡, 柯耀棠, 吳慧芬*, 表面修飾自組裝薄膜矽基質提升大氣壓基質輔助雷射游離質譜儀上的胜肽鑑定靈敏度.13屆分析技術交流研討會, 2007, May 26, 27, 清華大學.

l  Hui-Fen Wu*, Nanoparticle based - single drop microextraction for peptide analysis and drop to drop solvent microextraction to determine isomers in one drop of water, 2007, Mar. 6, 朝陽科技大學應化系演講.

l  Bih-Show Lou, Yuan-Chin Chen, Hui-Fen Wu*, Probing the Interaction of Na+ Channel Inactivation Gate Peptide in Linker between Domain III and IV and Phentoin by Using Electrospray Tandem Mass Spectrometry. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Jyh-Hao Yen, Hui-Fen Wu*, Drop to drop solvent microextraction coupled to AP-MALDI tandem mass spectrometry for rapid analysis of a drug from one drop of human urine and human plasma. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Kamlesh Shrivas, Hui-Fen Wu*, A simple and rapid quantitative method by direct coupling Drop-to-Drop Solvent Microextraction with Gas Chromatography/Mass Spectrometry to determine caffeine in one drop of beverages and foods. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Ramaiyen Sekar, Hui-Fen Wu*, A Simple and Fast Quantitative Method for Analysis of Monensin in Soil, Water and Urine by Direct Combining Single Drop Microextraction with Atmospheric Pressure–Matrix Assisted Laser Desorption/Ionization Mass Spectrometry, 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Hui-Fen Wu*, Chi-Hsein Lin, Combining single drop microextraction with AP-MALDI tandem mass spectrometry for rapid analysis of a peptide from biological samples. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Kamlesh Shrivas, Hui-Fen Wu*, Application of Atmospheric Pressure-Matrix Assisted Laser Desorption/Ionisation Mass Spectrometry in Simultaneous Quantitative Determination of Cationic Surfactants from River and Municipal Waste Water. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Hui-Fen Wu*, Jyh-Hao Yen, Developing a liquid phase microextraction method using a micropipet with disposable tips coupled to AP-MALDI tandem mass spectrometry for rapid drug analysis from biological matrixes. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Hsin-Yi Ku, Yuan-Chin Chen, Ja-Yi Yen, Hui-Fen Wu*, Separation and quantitative determination of tricyclic compounds by direct combining single-drop microextraction and micro-volume pipette extraction with Capillary electrophoresis techniques. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Hui-Fen Wu*, Chi-Hsien Lin, Direct combining immersed single drop microextraction with AP-MALDI tandem mass spectrometry for rapid analysis of a hydrophilic drug via hydrogen bonding interaction and comparison with LLE and LPME/DGM-HF. 95年化學年會, 2006, Dec., 淡江大學化學系.

l  Hui-Fen Wu*, Chi-Hsien Lin, Combining single drop microextraction with AP-MALDI tandem mass spectrometry for rapid analysis of a peptide from urine and plasma. 17th International Mass Spectrometry Conference, Prague, Czech Republic, Aug 27 - Sep 1, 2006.

l  Hui-Fen Wu*, Simple and Fast Analysis of Drugs by Direct Combining Single Drop Microextraction with AP-MALDI Mass Spectrometry. 2006臺灣質譜年會&學術研討會. 2006, June 22, 23, 中山大學. Invited Speaker.

l  Chen-Che Chin, Hui-Fen Wu*, Combining drop-to-drop solvent microextraction with gas chromatography/ion trap-mass spectrometry using electronic ionization method to develop a quantitative method. 2006臺灣質譜年會&學術研討會. 2006, June 22, 23, 中山大學.

l  Jyh-Hao Yen, Hui-Fen Wu*, Liquid phase microextraction using a micropipet with disposable tips coupled to AP-MALDI tandem mass spectrometry for rapid drug analysis from urine and human plasma. 2006臺灣質譜年會&學術研討會. 2006, June 22, 23, 中山大學.

l  Chi-Hsien Lin, Hui-Fen Wu*, Direct combining immersed single drop microextraction with AP-MALDI tandem mass spectrometry for rapid analysis of a hydrophilic drug via hydrogen bonding interaction and comparison with LLE and LPME/DGM-HF. 2006臺灣質譜年會&學術研討會. 2006, June 22, 23, 中山大學.

l  吳慧芬*,嚴哲毅,林其賢,秦偵哲,劉柏敏,賴秉葦, 液相微萃取法結合質譜進行環境污染物與藥物之微量分析. 2006臺灣質譜年會&學術研討會. 2006, June 22, 23, 中山大學.

l  Bih-Show Lou, Yuan-Chin Chen, Hui-Fen Wu*, 利用電灑質譜探討鈉離子通道在區域三和四之間的連結物在不活化狀態時的作用力. 2006臺灣質譜年會&學術研討會. 2006, June 22, 23, 中山大學.

l  Ramaiyen Sekar, Chen-Che Chin, Hui-Fen Wu*, A Simple and Fast Quantitative Method for Analysis of Monensin in Soil, Water and Urine by Direct Combining Single Drop Microextraction with Atmospheric Pressure–Matrix Assisted Laser Desorption/Ionization Mass Spectrometry, 13屆分析技術交流研討會, 2006, May 26, NKNU大學.

l  Hui-Fen Wu*, Nanoparticle assisted single drop microextraction coupled to atmospheric pressure matrix assisted laser desorption ion trap tandem mass spectrometry
for rapid analysis of peptides. 2006, Mar. 9,
成功大學化學系演講.

l  Hui-Fen Wu*, Nanoparticle assisted single drop microextraction coupled to AP-MALDI mass spectrometry for peptide analysis and drop to drop solvent microextraction coupled with GC/MS to determine isomers in one drop of water. 2006, Feb. 22, 中山大學化學系演講.

l  Hui-Fen Wu*, Nanoparticle assisted single drop microextraction coupled to AP-MALDI ion trap tandem mass spectrometry for rapid analysis of peptides. 2006, Feb. 18, 台灣大學化學系演講. Invited Speaker.

l  J. H. Yen, J. J. Chin, H. F. Wu*, DDSME/GC/EI/MS for quantification and DDSME/GC/SIMR/MS/MS/MS for isomer differentiation of methoxyacetophenone isomers in one drop of water and comparison with LLE, SDME, SPME and LPME/DGM-HF, 20051119-20, 中國化學會年會,中山大學.

l  H.-F. Wu*, P. Sudhir, Z. C. Zhou, Nanoparticles-assisted single drop microextraction (NPA-SDME) coupled with AP-MALDI mass spectrometry for peptide analysis, 20051119-20, 中國化學會年會,中山大學.

l  N. A. Khan, J. Y. Yan, H. F. Wu, Negative electrospray tandem mass spectrometry (MS2 to MS4) for probing the structures of acancer drug - flutamide extracted from pharmaceutical formulations by using Soxhlet apparatus, 20051119-20, 中國化學會年會,中山大學.

l P. Sudhir, H.-F. Wu*, Z. C. Zhou, A novel approach for the identification of peptides using gold nanoparticles-assisted single drop microextraction coupled with AP-MALDI mass spectrometry, 8th Asian Conference on Analytical Sciences, 94/10/16-20,台灣大學.

l B. W. Lai, B. M. Liu, H.-F. Wu*, Liquid-Phase Hollow Fiber Microextraction and Gas Chromatography/Negative Chemical Ionization Mass Spectrometry for the Determination of Dichlorophenol Isomers, 8th Asian Conference on Analytical Sciences, 94/10/16-20,台灣大學.

l Hui-Fen Wu*, Single drop microextraction, single drop nano particle microextraction, micro volume pipettor extraction and drop to drop solvent microextraction coupled to atmospheric pressure matrix assisted laser desorption/ionization ion trap tandem mass spectrometry for rapid analysis of drugs and biomolecules,台灣質譜學會2005年華人質譜學術交流研討會, 94616-17,大學. Invited Speaker.

l 林其賢,吳昭賢,吳慧芬*, 開發一滴溶劑微萃取法作為大氣壓基質輔助雷射脫附質譜法之濃縮探針以提高生化分子偵測的靈敏度.台灣質譜學會2005年華人質譜學術交流研討會, 94616-17,大學.

l 嚴哲毅,秦偵哲,吳慧芬*,一滴溶劑萃取一滴樣品之超微量萃取法連結大氣壓基質輔助雷射脫附質譜並作為藥物濃縮探針的開發,台灣質譜學會2005年華人質譜學術交流研討會, 94616-17,大學.

l C. H. Lin, J. H. Yen, H. F. Wu*, Understanding the surface reactivity of nanoparticles on formation of nanoscale cages of water clusters probed by electrospray / ion trap tandem mass spectrometry. 台灣質譜學會2005年華人質譜學術交流研討會, 94616-17,大學.

l C. H. Lin, H. F. Wu*, Combining single drop microextraction with AP-MALDI/ ion trap tandem mass spectrometry for rapid analysis of dopamine from urine and compared with LLE and LPME. 台灣質譜學會2005年華人質譜學術交流研討會, 94616-17,大學.

l J. H. Yen, C. H. Lin, B. M. Liu, H. F. Wu*, Physical adsorption of nanoscale cages of water clusters on the surfaces of iron and gold nano-particles investigated by electrospray / ion trap tandem mass spectrometry.11屆分析化學技術交流研討會2005/5/14, 淡江大學.

l C. H. Lin, H. F. Wu*, Combining single drop microextraction with atmospheric pressure matrix assisted laser desorption/ionization ion trap tandem mass spectrometry for rapid analysis of dopamine from urine. 11屆分析化學技術交流研討會2005/5/14, 淡江大學.

l P. Sudhir, H.-F. Wu*, Z. C. Zhou, An application of AP-MALDI and ESI tandem mass spectrometry to characterize the structure of a peptide, gramicidin and probing the interactions of gramicidin with divalent metallic salts using ESI-tandem mass spectrometry. 11屆分析化學技術交流研討會2005/5/14, 淡江大學.

l R. Sekar, H.-F. Wu*, Fast separation and determination of acetophenone and its mono hydroxyl positional isomer by capillary electrophoresis. 11屆分析化學技術交流研討會2005/5/14, 淡江大學.

l

l Hui-Fen Wu*, Application of ion trap mass spectrometry on self- ion/molecule reaction, ethylene diamine chemical ionization, single drop microextraction and electrospray ionization applied to drug analysis and gramicidin binding interaction with metal ions, 20041218-19,3屆兩岸分析化學會議, 大學, Invited Speaker.

l P. Sudhir, H.-F. Wu*, Z. C. Zhou, Probing the interactions of ion channel-gramicidin ionophores with divalent metallic cations (Ca+2, Mg+2, Zn+2) using electrospray tandem mass spectrometry. 931119-21,中國化學會年會,大學.

l P. Sudhir, H.-F. Wu*, Z. C. Zhou, Probing the interaction of kojic acid antibiotics with iron by using electrospray tandem mass spectrometry. 931119-21,中國化學會年會,大學.

l C.-H. Lin, B.-M. Liu, H.-F. Wu*, Formation of magic number of nano - water clusters by iron nano-particles detected by electrospray tandem mass spectrometry. 931119-21,中國化學會年會,大學.

l N. A. Khan, H.-F. Wu*, Analysis of silymarin extracted from commercial dosage forms by combining liquid-liquid extraction with negative electrospray tandem mass spectrometry. 931119-21,中國化學會年會,大學.

l C.-H. Lin, N. A. Khan, H.-F. Wu*, A rapid and efficient method to analyze the commercial ginseng mixtures by using electrospray tandem mass spectrometry. 931119-21,中國化學會年會,大學.

l 嚴哲毅, 劉柏敏, 吳慧芬*, 電灑質譜儀及固相微萃取結合氣相層析質譜於檢測血清中市售維他命E, 931119-21,中國化學會年會 ,大學.

l B. M. Liu, H. F. Wu*, Combining Single-Drop Microextraction with chemical ionization to detect anisaldehyde isomers in urine and blood. 931119-21,中國化學會年會 ,大學.

l L. C. Lu, N. A. Khan, H-F Wu*, Combining Single-Drop Microextraction with self-ion/molecule reaction to differentiate isomers in one drop of water solution. 931119-21,中國化學會年會,大學.

l H-F Wu*, C. H. Yan, N. A. Khan, Differentiation and quantification of xylene isomers by combining headspace solid phase microextraction, gas chromatography, Self-Ion Molecule Reaction and tandem mass spectrometry. 931119-21,中國化學會年會,大學.

l H. F. Wu*, C. H. Yan, A Single-Drop Microextraction method by combining a dual gauge microsyringe with a hollow fiber to detect pesticide in water. 931119-21,中國化學會年會,大學.

l B. M. Liu, B. W. Lai, H. F. Wu* Single-Drop Microextraction with a hollow fiber and Gas Chromatography/Electron Capture Detection Mass Spectrometry to detect dichlorophenols in urine. 931119-21,中國化學會年會,大學.

l N. A. Khan, L-C Lu, C-H Lin, B-M Liu, H-F Wu, Novel observation of Cluster ions of water by reactions of metallic nano-particles with water and organic solvents detected by electrospray mass spectrometry, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Nadeem Ahmad Khan, Li-Chi Lu, Hui-Fen Wu*, Electrospray Mass spectrometry as an important tool for probing the reaction mechanisms of oxidation of dopamine with potassium permanganate in basic medium, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Hui-Fen Wu*, Meng-Ting Wu, Chien-Hung Chen, Self - Ion / Molecule Reaction to produce the protonated molecules during collisionally activated dissociation in an ion trap, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l H-F Wu*, Pei-Yi Lin, Ethylene diamine as a novel liquid chemical reagent to probe the host guest interaction, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Wen-Feng Wu, Ya-Hsuen Lai, Hui-Fen Wu*, Differentiation of xylene isomers by SIMR, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l C-H Yan, C-H Lin, H-F Wu*, A Liquid-Phase Microextraction Method with a Dual Gauge Microsyringe, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Bo-Min Liu, Chi-Hsien Lin, Hui-Fen Wu*, Solvent Microextraction and Gas Chromatography/Chemical Ionization Mass Spectrometry to differentiate Anisaldehyde Isomers in Urine and Blood, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Bo-Min Liu, Bin-Wei Lai, Ja-Yi Yen, Hui-Fen Wu, Liquid-Phase Microextraction and Gas Chromatography / Negative Chemical Mass Spectrometry for the investigation of Dichlorophenol, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Nadeem Ahmad Khan, Chi-Hsien Lin, Ya-Yi Yen, Li-Chi Lu, Hui-Fen Wu, Electrospray mass spectrometry to probe oxidation of 2,4,5-trichlorophenol via KMnO4, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Wen - Feng Wu, Li-Chi Lu, Hui- Fen Wu*, Probing the unusual product ions observed in Self-Ion/Molecule Reactions of xylene isomers, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Nadeem Ahmad Khan, Li-Chi Lu, Hui-Fen Wu, A novel method to probe the drug oxidation reactions in acidic medium by combining ESI/MS and UV/Vis, 93年度台灣質譜學會年會, 93/6/15-16.台灣大學.

l Nadeem Khan, Li-Chi Lu, Chi-Hsien Lin, Bo-Min Liu, Hui-Fen Wu*, Study of metallic nano-particles to Clusters of water by using electrospray mass spectrometry, Taiwan International Conference on Nano Science and Technology,台灣奈米國際研討會, 93/6/30-7/3,清華大學.

l Hui-Fen Wu*, 1溶劑微萃取法及液相微萃取法結合氣相層析質譜的應用2自身離子/分子反應, June 11, 2004, Naitonal Chi-Nan大學化學系演講.

l Chi-Hsien Lin, Chih-Hao Yang, Hui-Fen Wu*, A Novel Liquid-Phase Microextraction Method : a Dual Gauge Microsyringe with a Hollow Fiber Membrane,第十屆分析化學技術交流研討會2004/5/8, 大學.

l 嚴哲毅,劉柏敏,吳慧芬*,利用固相微萃取法結合氣相層析質譜儀檢測市售藥物及血清中維他命E之混合物,第十屆分析化學技術交流研討會. 2004/5/8,大學.

l Bo-Min Liu, Bin-Wei Lai, H-F Wu, Combination of Liquid-Phase Hollow Fibre Membrane Microextraction with Gas Chromatography/Negative Chemical Ionization Mass Spectrometry for the Determination of Dichlorophenol Isomers in Environmental Sample,第十屆分析化學技術交流研討會2004/5/8, 大學.

l Bo-Min Liu, Hui-Fen Wu*, Single-Drop Microextraction and Gas Chromatography-Mass Spectrometric Determination of Anisaldehyde Isomers in Human Urine and Blood Serum,第十屆分析化學技術交流研討會2004/5/8, 大學.

l L. C. Lu, H. F. Wu*, Drop to drop solvent microextraction,第十屆分析化學技術交流研討會2004/5/8, 大學.

l Wen-Feng Wu, Hui-Fen Wu*, The first observation of methyne addition ions for xylene isomers in Self-Ion/Molecule Reactions for small aromatic compounds,第十屆分析化學技術交流研討會2004/5/8, 大學.

l Hui-Fen Wu*, Chi-Hsien Lin, Bo-Min Liu, Li-Chi Lu, Ja-Yi Yen, Ya-Hsuen Lai, Probing the reactions of metallic nanoparticles with organic compounds by electrospray mass spectrometry,第三屆海峽兩岸奈米科學與技術研討會2004 / 4/ 27- 5/1, P407, 東華大學.

l S J Dai, H F Wu,* F S Pan,藥物動力學:應用電灑法質譜儀結合液相層析儀快速偵測生物體血液及尿液,了解天然物之作用,開發新藥, 20031128-30,中國化學會年會 ,中原大學.

l 劉柏敏,吳慧芬*利用溶劑微萃取法結合氣相層析儀/化學游離法/串聯質譜鑑別及定量茴香醛結構異構物之混合物, 20031128-30,中國化學會年會 ,中原大學.

l 劉柏敏,賴秉葦,吳慧芬*, 液相微萃取結合氣相層析儀/串聯質譜在負離子化學游離法模式下區分及定量水、尿液及血清中之氯酚同分異構物, 20031128-30,中國化學會年會 ,中原大學.

l Mon-Tin Wu, Chien-Hung Chen, Hui-Fen Wu*, Novel observation of Self - Ion / Molecule Reaction during collisionally activated dissociation in an internal source ion trap mass spectrometer, 2003, 20031128-30, 中國化學會年會 ,中原大學.

l W. F. Wu, L. C. Lu , H. F. Wu*,Probing the Self-Ion/Molecule Reactions of xylene isomers by deuterium labeling and isolation experiments in an ion trap mass spectrometer, 20031128-30,中國化學會年會 ,中原大學.

l C. H. Yang, H. F. Wu*,Comparison of liquid phase microextraction, solvent microextraction and solid phase microextraction for determination of the organochlorine pesticides in water by Gas Chromatography/Ion Trap Mass Spectrometry, 20031128-30,中國化學會年會,中原大學.

l H. F. Wu*, J. H. Yen, C. C. Chin, Differentiation and quantitation of methoxyacetophenone isomers in one drop of water by combining drop to drop solvent microextraction, gas chromatograph, self ion/molecule reaction and tandem mass spectrometry, 20031128-30,中國化學會年會,中原大學.

l H. F. Wu*, Probing Self – Ion/Molecule Reactions in Ion Trap Mass Spectrometer, Proceedings of 2003 International Chemical Conference, Taipei Analytical Chemistry, 10/29-11/1. Invited Talk, L33.

l Wen-Feng Wu, Hui-Fen Wu*, Comparing differentiation of xylene isomers by electronic ionization, chemical ionization and Self-Ion/Molecule Reactions and the first observation of methyne addition ions for xylene isomers in Self-Ion/Molecule Reactions for non-nitrogenated compounds, Proceedings of 2003 International Chemical Conference, Taipei Analytical Chemistry., 10/29-11/1, 59.

l Pei-Yi Lin, Hui-Fen Wu*, Probing the Effects of Reagent Gas Pressure and Ion Source Temperature for Dimethyl Ether Chemical Ionization of Tricyclic Antidepressants in an External Source Ion Trap Mass Spectrometer, Proceedings of 2003 International Chemical Conference, Taipei Analytical Chemistry., 10/29-11/1, 58.

l Yen-Ren Chen, Bin-Wei Lai, Hui-Fen Wu*, Study the effects of total ion chromatogram  splitting in the Ion Trap Mass Spectrometer, International Chemical Conference, Taipei Analytical Chemistry., 2003, 10/29-11/1, p57.

l Hui-Fen Wu*, 溶劑微萃取法及固相微萃取法結合自身離子/分子反應於離子阱串聯質譜儀中的應用及正/負化學游離法的研究, Sep. 5, 2003,成功大學化學系演講.

l Leo Brewer, Karen Krushwitz, Robert Lamoreaux, Hui-Fen Wu, Thermodynamics of Alloys, Rome, Italy, Sep. 8-13, 2002.

l C.H. Yang, H. F. Wu*,利用頂空式固相微萃取法/氣相層析離子阱串聯質譜儀偵測水中二甲苯及研發以自身離子/分子反應進行同分異構物鑑別之新方法, 20021025-27, 中油,中國化學會年會, paper No.P-AN-047.

l Hui-Fen Wu*, Wen-Feng Wu, Probing the Reaction Mechanism for Methylene Addition Reaction of O, M, P-Xylenes in the Self–Ion/ Molecule Reactions and Differentiation of Xylene Isomers by Several Ion Trap Mass Spectrometric Techniques. 20021025-27, 中油,中國化學會年會, paper No.P-AN-046.

l Hui-Fen Wu*, Wen-Feng Wu, Probing the Reaction Mechanism for Methylene Addition Reaction of O, M, P-Xylenes in the Self–Ion/ Molecule Reactions and Differentiation of Xylene Isomers by Several Ion Trap Mass Spectrometric Techniques. 20021025-27, 中油,中國化學會年會, paper No.P-AN-046.

l Hui-Fen Wu*, Shan-Min Huan, Chan-Fu Wu and Mon-Tin Wu, 2002, Molecular Modelling and Electrospray Mass Spectrometry for Probing Host-Guest Interaction of Metal Ions with Bis[(benzo-15-crown-5)-15-ylmethyl]pimelate. 20021025-27, 中油,中國化學會年會, paper No.P-AN-044.

l Hui-Fen Wu*, Chien-Hung Chen and Bin-Wei Lai, Unusual Adduct Ions Attachment in Negative Chemical Ionization and Collisionally Activated Dissociation in an Ion Trap. 20021025-27, 中油,中國化學會年會, paper No.P-AN-045.

l Hui-Fen Wu*, Yu-Jie Chuan, A Novel Method for Isomer Differentiation by Combining Gas Chromatograph, Selective Self–Ion/ Molecule Reaction and Tandem Mass Technique  in an Ion Trap Mass Spectrometer. 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, ThPQ351. 200262-6

l Bin-Wei Lai, Hui-Fen Wu*, SelfIon/ Molecule Reactions for Negative Ions in an External Source Ion Trap Tandem Mass Spectrometer, 20025/10,分析技術研討會,弘光技術學院, B8.

l Hui-Fen Wu*, Chien-Hung Chen, Probing the Reaction Mechanisms of Selective Self - Ion / Molecule Reaction for dopamine in an Internal Source Ion Trap Mass Spectrometer, 20011228-30,成功大學,中國化學會年會, paper No.P3-AN-037, page AN-38.

l Hui-Fen Wu*, Yu-Jie Chuan, A Novel Method for Isomer Differentiation in an Ion Trap Mass Spectrometer, 20011228-30,成功大學,中國化學會年會, paper No.P3-AN-032, page AN-37.

l Hui-Fen Wu*, Mao-Jun Chun, Examination of Uracil Compounds by Electron Capture Detection and Collisional Activated Dissociation in the External Source Ion Trap, 20011228-30,成功大學,中國化學會年會, paper No.P3-AN-050, page AN-41.

l Hui-Fen Wu*, Chao-Chin Wu, “Probing the Reaction Patterns for Negative Chemical Ionization of Phthalic Anhydride and Related Compounds in an External Source Ion Trap Mass Spectrometer”, 20011228-30,成功大學,中國化學會年會, paper No.P3-AN-029, page AN-36.

l Hui-Fen Wu*, Shun-Min Huan and Chan-Fu Wu, Conformation Analysis and Binding Affinity Determination for Host-Guest Complexation of Alkali Metal Ion with Bis (Crown Ether)s by Electrospray Mass Spectrometry, 20011228-30,成功大學,中國化學會年會, paper No.P3-AN-038, page AN-38.

l Hui-Fen Wu* and Pei-Yi Lin, “Investigating the Pressure and Temperature Effect for Dimethyl Ether Chemical Ionization of Tricyclic Antidepressants in an External Source Ion Trap Tandem Mass Spectrometer”, 20011228-30,成功大學,中國化學會年會, paper No.P2-AN-016, page AN-18.

l Hui-Fen Wu* and Pei-Yi Lin, “Study of the Effects of Temperature Parameters on the Positive Chemical Ionization Spectra in Ion Trap Mass Spectrometer”, 20011228-30,成功大學,中國化學會年會, paper No.P3-AN-026, page AN-35.

l Hui-Fen Wu*, Li-Wei Chen and Chien-Hung Chen, Probing the Reactive Sites for Ion/Molecule Reactions of Anthraquinones with Dimethyl Ether by an External Source Ion Trap Tandem Mass Spectrometer and Computational Chemistry, 20011228-30,成功大學,中國化學會年會, paper No.P3-AN-035, page AN-37.

l Hui-Fen Wu*, Chien-Hung Chen, Yu-Jie Chuang, Hsiao-Wei Li and Wen-Fon Wu, 20011020-21, “Study of Self – Ion/Molecule Reactions in Bench-top Ion Trap Mass Spectrometer”,第二屆兩岸分析化學會議, 北京,清華大學, Invited Speaker, p215.

l Hui-Fen Wu*, Shiuan-Ming Huang, Chang-Fu Wu, 2001722-26, “Synthesis of Host – Guest Complexes by Electrospray Ionization Mass Spectrometry” 11th IUPAC Syposium on Organiometallic Chemistry Directed Towards Organic Synthesis, Taipei, Yuan-Sun Hotel, p216.

l Hui-Fen Wu*, Pei-Yi Lin, 200161-2, “Investigating the Effects of Some Basic Temperature Parameters on A Powerful Instrument for Enviromental Research - the Ion Trap Tandem Mass Spectrometer” 2001年環境分析化學研討會, 淡江大學, p41.

l Hui-Fen Wu*, Ming-Yi Ho and Chien-Hung Chen, 2001527-31, “Selective Self - Ion / Molecule Reactions in Ion Trap Mass Spectrometer”, 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago, IL, ThP 046.

l Hui-Fen Wu*, Chien-Hung Chen and Ming-Yi Ho, 2001427,“Study of the Best Pressure Range for Ion/Molecule Reactions of Anthraquinones in an Ion Trap Mass Spectrometer with an External Source” 2001年分析技術研討會, 正修技術學院, p28.

l 吳慧芬*, 200116,“離子質譜儀的正/負化學游離法之溫度,壓力效應,串聯質譜靈敏度的測量與自身離子/分子反應的研發”,淡江尖端化學系列研討會-質譜,淡江大學, Invited Talk, page 6-8.

l Hui-Fen Wu*, Ming-Yi Ho, Chien-Hong Chen, 20001124-26, “Study of Pressure Effect for Dimethyl Ether Chemical Ionization in an External Source Ion Trap” ,中國化學會年會,台中, 靜宜大學, paper No.P-2A-AN-012, page AN-50.

l 吳慧芬*, 2000617-18,“Examination of Pressure and Temperature Effect of Electron Capture Detection Mass Spectrometry in an External Source Ion Trap”, 第一屆兩岸分析化學暨第八屆分析化學技術交流研討會,新竹, 清華大學, paper No.P-43, page 182.

l 吳慧芬*,林雅萍, 2000617-18, “Examination of the Collisional Cooling Effect for Two and Three Kinds of Mixed Buffer Gases in an Internal Source Ion Trap”, 第一屆兩岸分析化學暨第八屆分析化學技術交流研討會,新竹,清華大學, paper No.P-27, page 166.

l 吳慧芬*,林雅萍,林佩怡,陳建弘, 19991119-20, “冠狀醚與二甲基離子反應的研究”,中國化學會年會,台北國際會議中心, paper No.P-AN-003, page 37.

l 吳慧芬*,林雅萍, 19991119-20, “以離子串聯質譜儀之正/負化學游離法進行嘌呤類化合物的分析”,中國化學會年會,台北國際會議中心, paper No.P-AN-004, page 37.

l Hui-Fen Wu*, Chao-Ching Wu, 1999, “Study of Temperarure and Pressure Effect of Phthalic Anhydride by Negative Ion Analysis Using Methane and Oxygen as Reagent Gases in an Ion Trap Tandem Mass Spectrometer”. Eighth Asian Chemical Congress, Taipei, Nov.21-24, paper No. O-A-14, page 134.

l Hui-Fen Wu* and Ya-Ping Lin, 1999, “Determination of Sensitivity of the External Source Ion Trap Tandem Mass Spectrometer Using Dimethyl Ether Chemical Ionization”. Eighth Asian Chemical Congress (8ACC), Taipei, Nov.21-24, paper No. P-A-54, page 201.

l Hui-Fen Wu* and Miao-Chun Chung, 1999,“Characterization of Uracil Compounds and their derivatives by Negative Ion Analysis in an Ion Trap Tandem Mass Spectrometer” 7屆分析化學技術交流研討會,台中,靜宜大學, May 16-17, page 28.

l Hui-Fen Wu* and Chao-Ching Wu, 1999,“Characterization of Phthalic Anhydride and their Derivatives by Electron Capture Detection/Collisional Activated Dissociation in Ion Trap Mass Spectrometer with an External Ionization Source” 7屆分析化學技術交流研討會,台中,靜宜大學, May 16-17, page 33.

l Hui-Fen Wu* and Li-Wei Chen, “Combined Ion/Molecule Reactions and Tandem Mass Spectrometric Techniques for the Characterization of Anthraquinones in an External Ionization Ion Trap Mass Spectrometer”. Proceedings of 1999 International Chemical Conference, Taipei Analytical Chemistry. May 12-15, page 3.

l Hui-Fen Wu* and Ya-Ping Lin, 1999, “Study of Reaction Mechanisms for Ion-Molecule Reactions and Collisionally Activated Dissociation of Dopamine and Adrenaline by an Ion Trap Mass Spectrometer with an External Ionization Source” Proceedings of 1999 International Chemical Conference, Taipei Analytical Chemistry. May 12-15, page 5.

l Hui-Fen Wu*, Li-Wei Chen and Ya-Ping Lin, 1999, “Simulation of Collisional Cooling Effect in a Quadrupole Ion Trap Mass Spectrometer”. Proceedings of 1999 International Chemical Conference, Taipei Analytical Chemistry. May 12-15, page 4.

l 吳慧芬*,林雅萍, 1998,1127-29, “DopamineNortriptyline與二甲基離子的氣相離子/分子反應的溫度效應之研究”, 中正大學,中國化學會年會, paper No.P-1b-AN-084, page 90.

l 吳慧芬*,吳朝欽, 1998,1127-29, “黃素母酮類藥物在離子質譜儀中之離子/分子反應”, 中正大學,中國化學會年會, paper No.P-1b-AN-085, page 91.

l 吳慧芬*,鍾淼, 1998,1127-29, “三環系抗鬱劑藥物與二甲基離子之離子/分子反應”, 中正大學,中國化學會年會, paper No.P-1b-AN-083, page 90.

l 吳慧芬*,陳立偉,1998, 五月二日,“模擬離子質譜儀混合之緩衝氣體的碰撞冷卻效應”. 第六屆分析化學技術交流研討會, 屏東大仁藥專, page E14.

l 吳慧芬*, 陳立偉,1998, 五月二日, “恩昆類藥物與二甲基離子的氣相離子-分子反應”. 第六屆分析化學技術交流研討會, 屏東大仁藥專, page E4.

l 吳慧芬*, 林雅萍, 1998, 五月二日, “兒茶酚胺類藥物與二甲基離子之氣相離子-分子反應”. 第六屆分析化學技術交流研討會, 屏東大仁藥專, page E5.

l Hui-Fen Wu*, Li-Wei Chen, 1997, Dec. 5-7, “Host-Guest Complexation of Alkaline Earth Metal Ions, Aluminum Ions and Transition Metal Ions with Crown Ethers by Fast Atom Bombardment Mass Spectrometry”, 中國化學會年會, 新竹, paper No.P-2-AN-035, page 179.

l 吳慧芬*,陳立偉,鍾淼,吳朝欽,林雅萍, 1997, Dec. 5-7, “理論計算模擬離子質譜儀中的碰撞冷卻效應”, 中國化學會年會,新竹,paper No.P-2-AN-145, page 234.

l Hui-Fen Wu*, Leo Brewer ,1997, Dec. 5-7, “Parameters for Calculation of Properties of Acid-Base Intermetallies in Brewer-Engel Theory”, 中國化學會年會, 新竹, paper No. P-1-IN-014, page 80.

l Hui-Fen Wu*, 1997, May,“Gas-Phase Ion/Molecule Reactions in a Quadrupole Ion Trap Mass Spectrometry”. 交通大學,第五屆分析化學技術交流研討會,May 3,p I-3. Invited Speaker.

l Hui-Fen Wu*, Leo Brewer, “Calculation of Thermodynamic Effect of  the Brewer-Engel Generalized Acid-Base Reactions of the 1:1 Intermetallics for Nontransition Metals Al, Mg with Transition Metals:中國化學會年會,鳳山陸軍官校, 1996, Dec. 6-7, paper No.P-1-PH-15,page 223.

l Karen Krushwitz, Leo Brewer, Hui-Fen Wu, “New Materials for Emerging Giant: Brewer-Engel Model for China in the 21st Century”. Gordon Conference: High-Temperature Chemistry, Tilton, New Hampshire, 1996, July 21-26.